Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 7/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2980097 | 0.82 | CES2 (0.65) | AKR1C3AKR1C2NPSR1TSHRBLM | |
| SCHEMBL2980094 | 0.82 | CES2 (0.65) | AKR1C3AKR1C2NPSR1TSHRBLM | |
| SCHEMBL7094007 | 0.82 | CES2 (0.65) | AKR1C3AKR1C2NPSR1TSHRBLM | |
| SCHEMBL11437729 | 0.82 | BLM (0.51) | AKR1C3AKR1C2NPSR1TSHRBLM | |
| SCHEMBL11475491 | 0.82 | BLM (0.51) | AKR1C3AKR1C2NPSR1TSHRBLM | |
| SCHEMBL29009775 | 0.80 | AKR1C3 (0.54) | AKR1C3AKR1C2NPSR1TSHRLMNA | |
| SCHEMBL9987950 | 0.79 | BLM (0.57) | AKR1C3AKR1C2NPSR1TSHRBLM | |
| SCHEMBL3840793 | 0.79 | BLM (0.57) | NPSR1TSHRBLMLMNAMAPK1 | |
| SCHEMBL9987952 | 0.79 | BLM (0.57) | AKR1C3AKR1C2NPSR1TSHRBLM | |
| SCHEMBL11478613 | 0.79 | BLM (0.57) | NPSR1TSHRBLMLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025242872-A1 | 1H-PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES | Apollo AP45 Limited (GB) | 2025-11-27 | — | — | WO | disclosed |