Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 4/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | PPID | Q08752 | 5/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | PPIG | Q13427 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31737934 | 0.90 | PPIB (0.52) | PPIBPPIAPPIDPPIG | |
| SCHEMBL31738253 | 0.90 | PPIB (0.52) | PPIBPPIAPPIDPPIG | |
| SCHEMBL31738169 | 0.90 | PPIB (0.52) | PPIBPPIAPPIDPPIG | |
| SCHEMBL31737997 | 0.89 | PPIB (0.46) | PPIBPPIAPPIDPPIGNPC1 | |
| SCHEMBL31737964 | 0.87 | PPIB (0.41) | PPIBPPIAPPIDPPIG | |
| SCHEMBL31738072 | 0.85 | PPIB (0.40) | PPIBPPIAPPIDPPIGLMNA | |
| SCHEMBL31737986 | 0.85 | HTR1A (0.43) | PPIBPPIASMN1; SMN2ALDH1A1 | |
| SCHEMBL31737551 | 0.85 | PPIB (0.42) | PPIBPPIAPPIDPPIG | |
| SCHEMBL31738176 | 0.84 | PPIB (0.39) | PPIBPPIAPPIDPPIG | |
| SCHEMBL31738031 | 0.82 | PPIB (0.46) | PPIBPPIAPPIDPPIG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025243042-A1 | COMPOUNDS FOR THE INHIBITION OF CYCLOPHILIN D | THE UNIVERSITY OF LIVERPOOL (GB) | 2025-11-27 | — | — | WO | claimed |
| WO-2025243042-A1 | COMPOUNDS FOR THE INHIBITION OF CYCLOPHILIN D | THE UNIVERSITY OF LIVERPOOL (GB) | 2025-11-27 | — | — | WO | disclosed |