Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | TP53 | P04637 | 5/20 | 0.50 |
| ▸ | AURKA | O14965 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | INSR | P06213 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22543309 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTTP53AURKAPOLB | |
| SCHEMBL29774507 | 0.92 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTTP53POLBLMNA | |
| SCHEMBL17240563 | 0.92 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTTP53POLBLMNA | |
| SCHEMBL20570336 | 0.91 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTTP53AURKAPOLB | |
| SCHEMBL30754768 | 0.89 | GAA (0.57) | SMN1; SMN2MAPTTP53AURKAPOLB | |
| SCHEMBL22542867 | 0.89 | GAA (0.57) | SMN1; SMN2MAPTTP53AURKAPOLB | |
| SCHEMBL22542704 | 0.88 | MAPT (0.54) | SMN1; SMN2MAPTTP53POLBLMNA | |
| SCHEMBL31741917 | 0.88 | MAPT (0.54) | SMN1; SMN2MAPTTP53POLBLMNA | |
| SCHEMBL22542872 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTTP53POLBLMNA | |
| SCHEMBL30754719 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTTP53POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3630115-B1 | COMPOSITIONS AND METHODS FOR PREPARING AND USING MITOCHONDRIAL UNCOUPLERS | UNIV VIRGINIA PATENT FOUNDATION (US) | 2025-12-10 | — | — | EP | disclosed |