SCHEMBL31742406

SCHEMBL31742406

CC(C)(C)c1ccc2c(c1)c1cc(C(C)(C)C)ccc1n2-c1ccc2c3cc(C(C)(C)C)cc4c5ccc(-n6c7ccc(C(C)(C)C)cc7c7cc(C(C)(C)C)ccc76)nc5n(c2n1)c34

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PGR P06401 1/20 0.33
▸ RORA P35398 1/20 0.33
▸ RORC P51449 1/20 0.33
▸ RORB Q92753 1/20 0.33
▸ HTR1D P28221 1/20 0.33
▸ KCNH2 Q12809 1/20 0.31
▸ NR1I2 O75469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31742405 0.78 TRPV1 (0.32) PGRRORARORCRORBHTR1D
SCHEMBL24412640 0.77 HTR1D (0.38) PGRRORARORCRORBHTR1D
SCHEMBL24412312 0.76 HTR1D (0.37) PGRRORARORCRORBHTR1D
SCHEMBL30261089 0.76 HTR1D (0.39) PGRRORARORCRORBHTR1D
SCHEMBL20857858 0.75 HTR1D (0.41) PGRRORARORCRORBHTR1D
SCHEMBL20857875 0.72 HTR1D (0.44) PGRRORARORCRORBHTR1D
SCHEMBL20857917 0.72 HTR1D (0.44) PGRRORARORCRORBHTR1D
SCHEMBL23204630 0.72 KIF11 (0.37) PGRRORARORCRORBHTR1D
SCHEMBL24822768 0.72 HTR1D (0.39) PGRRORARORCRORBHTR1D
SCHEMBL31742408 0.71 KIF11 (0.47) PGRRORARORCRORBHTR1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250380566-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-12-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250380566-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, PDCD2L PGR 2612/4885RORA 1638/4885RORC 1111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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