Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNPO | Q9NVS9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | PDXK | O00764 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21916335 | 1.00 | PNPO (0.41) | PNPOALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL31746185 | 0.93 | PNPO (0.40) | PNPOALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL16013626 | 0.93 | PNPO (0.40) | PNPOALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL21916175 | 0.91 | PNPO (0.39) | PNPOALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL21916341 | 0.84 | HDAC1 (0.35) | PNPOALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL21916597 | 0.84 | HDAC1 (0.35) | PNPOALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL31746195 | 0.81 | PNPO (0.39) | PNPOALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL20502644 | 0.81 | PNPO (0.39) | PNPOALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL21916188 | 0.81 | PNPO (0.39) | PNPOALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL20143334 | 0.81 | HPGD (0.50) | PNPOALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12503553-B2 | Biodegradable drug-polymer conjugate | POLYACTIVA PTY LTD (AU) | 2025-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12503553-B2 | Biodegradable drug-polymer conjugate | ADRB3, PTGER3, CHRNE | PNPO 1542/4885ALDH1A1 1039/4885HPGD 881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.