Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.39 |
| ▸ | PDXK | O00764 | 1/20 | 0.39 |
| ▸ | PNPO | Q9NVS9 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20143333 | 0.93 | KDM4E (0.61) | HPGDALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL5346682 | 0.93 | KDM4E (0.61) | HPGDALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL16769247 | 0.90 | ALDH1A1 (0.40) | HPGDALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL1546086 | 0.84 | KDM4E (0.49) | HPGDALDH1A1KDM4EHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL1546007 | 0.83 | KDM4E (0.47) | HPGDALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL16769248 | 0.83 | KDM4E (0.49) | HPGDALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL483438 | 0.81 | DGKA (0.43) | HPGDALDH1A1KDM4EHSD17B10HDAC1 | |
| SCHEMBL21916335 | 0.81 | PNPO (0.41) | HPGDALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL31746196 | 0.81 | PNPO (0.41) | HPGDALDH1A1KDM4EHSD17B10LMNA | |
| SCHEMBL2905259 | 0.81 | DGKA (0.43) | HPGDALDH1A1KDM4EHSD17B10HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968684-B2 | Polymer-NSAID conjugate | POLYACTIVA PTY LTD (AU) | 2018-05-15 | — | — | US | disclosed |