SCHEMBL31746921

SCHEMBL31746921

Cn1ncc2cc(Nc3cccc4ccn(CC(=O)NCC(F)(F)F)c(=O)c34)cnc21

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 1/20 0.37
KMT2A Q03164 3/20 0.36
POLB P06746 3/20 0.36
KDM4E B2RXH2 3/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MEN1 O00255 2/20 0.35
LMNA P02545 3/20 0.35
NPC1 O15118 1/20 0.34
TP53 P04637 1/20 0.34
USP2 O75604 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
RAB9A P51151 2/20 0.33
FGFR3 P22607 1/20 0.33
KDR P35968 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25073893 1.00 MALT1 (0.37) MALT1KMT2APOLBKDM4EL3MBTL1
SCHEMBL25073849 0.89 KMT2A (0.35) KMT2APOLBKDM4EL3MBTL1MEN1
SCHEMBL31746951 0.89 KMT2A (0.35) KMT2APOLBKDM4EL3MBTL1MEN1
SCHEMBL30279213 0.88 NOTUM (0.38) KMT2AKDM4EMEN1NPC1TP53
SCHEMBL25073876 0.88 NOTUM (0.38) KMT2AKDM4EMEN1NPC1TP53
SCHEMBL25073852 0.87 KDM4E (0.36) KMT2APOLBKDM4EMEN1LMNA
SCHEMBL31746950 0.87 KDM4E (0.36) KMT2APOLBKDM4EMEN1LMNA
SCHEMBL25073806 0.87 CACNA1H (0.35) MALT1KMT2APOLBKDM4EL3MBTL1
SCHEMBL25073888 0.86 KMT2A (0.36) KMT2APOLBKDM4EL3MBTL1MEN1
SCHEMBL25073904 0.86 NAMPT (0.36) MALT1KMT2APOLBFGFR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4387963-B1 PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 REDX PHARMA LTD (GB) 2025-12-24 EP disclosed