SCHEMBL31746951

SCHEMBL31746951

Cn1ncc2ncc(Nc3cccc4ccn(CC(=O)NCC(F)(F)F)c(=O)c34)cc21

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.35
KDM4E B2RXH2 2/20 0.35
POLB P06746 3/20 0.34
MEN1 O00255 2/20 0.34
GRIN2B Q13224 3/20 0.34
LMNA P02545 3/20 0.34
NPC1 O15118 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
USP2 O75604 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25073849 1.00 KMT2A (0.35) KMT2AKDM4EPOLBMEN1GRIN2B
SCHEMBL25073852 0.89 KDM4E (0.36) KMT2AKDM4EPOLBMEN1LMNA
SCHEMBL31746950 0.89 KDM4E (0.36) KMT2AKDM4EPOLBMEN1LMNA
SCHEMBL31746921 0.89 MALT1 (0.37) KMT2AKDM4EPOLBMEN1LMNA
SCHEMBL25073893 0.89 MALT1 (0.37) KMT2AKDM4EPOLBMEN1LMNA
SCHEMBL25073876 0.87 NOTUM (0.38) KMT2AKDM4EMEN1NPC1ALDH1A1
SCHEMBL30279213 0.87 NOTUM (0.38) KMT2AKDM4EMEN1NPC1ALDH1A1
SCHEMBL31746904 0.84 KDM4E (0.34) KMT2AKDM4EPOLBMEN1LMNA
SCHEMBL25073851 0.84 KDM4E (0.34) KMT2AKDM4EPOLBMEN1LMNA
SCHEMBL25073913 0.83 DDR1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4387963-B1 PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 REDX PHARMA LTD (GB) 2025-12-24 EP disclosed