Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25073758 | 1.00 | IRAK4 (0.40) | IRAK4MAPK1NOTUMNTSR1NPC1 | |
| SCHEMBL31746903 | 0.91 | GRIN2B (0.41) | IRAK4NOTUMNTSR1NPC1ALDH1A1 | |
| SCHEMBL31746965 | 0.91 | GRIN2B (0.41) | IRAK4NOTUMNTSR1NPC1ALDH1A1 | |
| SCHEMBL25073780 | 0.91 | GRIN2B (0.41) | IRAK4NOTUMNTSR1NPC1ALDH1A1 | |
| SCHEMBL25073854 | 0.91 | GRIN2B (0.41) | IRAK4NOTUMNTSR1NPC1ALDH1A1 | |
| SCHEMBL31746907 | 0.91 | GRIN2B (0.41) | IRAK4NOTUMNTSR1NPC1ALDH1A1 | |
| SCHEMBL25073916 | 0.91 | GRIN2B (0.41) | IRAK4NOTUMNTSR1NPC1ALDH1A1 | |
| SCHEMBL25073747 | 0.88 | NOTUM (0.37) | IRAK4NOTUMNTSR1NPC1ALDH1A1 | |
| SCHEMBL25073924 | 0.88 | NTSR1 (0.38) | IRAK4MAPK1NOTUMNTSR1NPC1 | |
| SCHEMBL25073749 | 0.88 | IRAK4 (0.37) | IRAK4NOTUMNTSR1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387963-B1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA LTD (GB) | 2025-12-24 | — | — | EP | disclosed |