Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25073750 | 1.00 | NOTUM (0.43) | NOTUMKDM4EMAPK1POLBNTRK1 | |
| SCHEMBL25073817 | 0.92 | POLB (0.49) | NOTUMKDM4EMAPK1POLBPSMB5 | |
| SCHEMBL31746888 | 0.92 | POLB (0.49) | NOTUMKDM4EMAPK1POLBPSMB5 | |
| SCHEMBL25073746 | 0.92 | KDM4E (0.48) | NOTUMKDM4EMAPK1POLBPSMB5 | |
| SCHEMBL31746886 | 0.90 | NOTUM (0.41) | NOTUMKDM4EPOLBNTRK1NTSR1 | |
| SCHEMBL25073820 | 0.90 | NOTUM (0.41) | NOTUMKDM4EPOLBNTRK1NTSR1 | |
| SCHEMBL31746956 | 0.89 | NOTUM (0.42) | NOTUMKDM4EPOLBNTRK1NTSR1 | |
| SCHEMBL25073855 | 0.89 | NOTUM (0.42) | NOTUMKDM4EPOLBNTRK1NTSR1 | |
| SCHEMBL25073779 | 0.87 | KDM4E (0.47) | NOTUMKDM4EMAPK1NTSR1ALDH1A1 | |
| SCHEMBL31746968 | 0.87 | KDM4E (0.47) | NOTUMKDM4EMAPK1NTSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387963-B1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA LTD (GB) | 2025-12-24 | — | — | EP | disclosed |