Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25073772 | 1.00 | NLRP3 (0.38) | NLRP3POLBLMNAALDH1A1L3MBTL1 | |
| SCHEMBL31162661 | 0.86 | MAPT (0.43) | NLRP3POLBLMNAALDH1A1L3MBTL1 | |
| SCHEMBL31746908 | 0.85 | KDR (0.45) | NLRP3POLBLMNAKMT2ARXFP1 | |
| SCHEMBL25073769 | 0.85 | KDR (0.45) | NLRP3POLBLMNAKMT2ARXFP1 | |
| SCHEMBL31746882 | 0.85 | NLRP3 (0.41) | NLRP3POLBLMNAALDH1A1L3MBTL1 | |
| SCHEMBL25073807 | 0.85 | NLRP3 (0.41) | NLRP3POLBLMNAALDH1A1L3MBTL1 | |
| SCHEMBL25073905 | 0.84 | MAPK8 (0.38) | NLRP3ALKKMT2A | |
| SCHEMBL31746899 | 0.84 | MAPK8 (0.38) | NLRP3ALKKMT2A | |
| SCHEMBL25073889 | 0.82 | KMT2A (0.37) | NLRP3POLBLMNAALDH1A1MEN1 | |
| SCHEMBL31746887 | 0.82 | KMT2A (0.37) | NLRP3POLBLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387963-B1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA LTD (GB) | 2025-12-24 | — | — | EP | disclosed |