Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | NEK1 | Q96PY6 | 5/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 3/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | SDHB | P21912 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13267260 | 0.85 | ROCK2 (0.54) | SCDROCK2CA12CA1CA2 | |
| SCHEMBL30042393 | 0.83 | ROCK2 (0.48) | SCDROCK2 | |
| SCHEMBL23649111 | 0.83 | ROCK2 (0.48) | SCDROCK2 | |
| SCHEMBL17998107 | 0.82 | SCD (0.44) | SCDROCK2 | |
| SCHEMBL3093032 | 0.81 | ROCK2 (0.50) | GABRG2GABRB3GABRA5GABRA3SCD | |
| SCHEMBL23804708 | 0.81 | SCD (0.49) | SCDROCK2USP30 | |
| SCHEMBL16005879 | 0.81 | SLC2A1 (0.43) | SCDROCK2PDK2USP30 | |
| SCHEMBL25445548 | 0.81 | ROCK2 (0.56) | GABRG2GABRB3GABRA5GABRA3SCD | |
| SCHEMBL17438000 | 0.81 | SCN9A (0.45) | SCDROCK2PDK2USP30 | |
| SCHEMBL29043852 | 0.79 | ROCK2 (0.43) | SCDROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262297-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2025-12-26 | — | — | WO | disclosed |
| EP-4667467-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | Dark Blue Therapeutics Ltd (GB) | 2025-12-24 | — | — | EP | disclosed |