Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.46 |
| ▸ | SCN4A | P35499 | 6/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16709634 | 0.86 | KEAP1 (0.49) | SCN4ASCN9AJAK2JAK1PIK3CA | |
| SCHEMBL4183271 | 0.79 | CFTR (0.47) | FYNPIK3CAATR | |
| SCHEMBL16709594 | 0.79 | SCN4A (0.59) | SCN4A | |
| SCHEMBL29938346 | 0.76 | SCN9A (0.43) | SCN4ASCN9AFYNMAP2K4 | |
| SCHEMBL306662 | 0.73 | HSP90AA1 (0.39) | GPR119SCN9APIK3CA | |
| SCHEMBL29938426 | 0.73 | SMARCA2 (0.43) | SCN4AGPR119SCN9A | |
| SCHEMBL3938235 | 0.73 | SMARCA2 (0.43) | SCN4AGPR119SCN9A | |
| SCHEMBL30444814 | 0.72 | RIPK2 (0.46) | MKNK2MAPKAPK2JAK2 | |
| SCHEMBL28155365 | 0.71 | BCHE (0.37) | GPR119MAP2K4PIK3CA | |
| SCHEMBL2959354 | 0.71 | BCHE (0.38) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262297-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2025-12-26 | — | — | WO | disclosed |
| EP-4667467-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | Dark Blue Therapeutics Ltd (GB) | 2025-12-24 | — | — | EP | disclosed |