Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 4/20 | 0.71 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 3/20 | 0.58 |
| ▸ | TTR | P02766 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18601896 | 0.86 | ELANE (0.59) | BCL2MCL1MAPTMEN1KMT2A | |
| Rubiadin SCHEMBL1426928 | 0.86 | BCL2 (0.71) | BCL2MCL1MAPTMEN1KMT2A | |
| Rubiadin SCHEMBL29665059 | 0.86 | BCL2 (0.71) | BCL2MCL1MAPTMEN1KMT2A | |
| Rubiadin SCHEMBL30260037 | 0.86 | BCL2 (0.71) | BCL2MCL1MAPTMEN1KMT2A | |
| Rubiadin SCHEMBL22616292 | 0.86 | BCL2 (0.71) | BCL2MCL1MAPTMEN1KMT2A | |
| SCHEMBL3191858 | 0.85 | ELANE (0.67) | BCL2MCL1MAPTMEN1KMT2A | |
| SCHEMBL555230 | 0.83 | BCL2 (1.00) | BCL2MCL1MAPTMEN1KMT2A | |
| SCHEMBL29388375 | 0.83 | BCL2 (1.00) | BCL2MCL1MAPTMEN1KMT2A | |
| SCHEMBL29384381 | 0.83 | BCL2 (1.00) | BCL2MCL1MAPTMEN1KMT2A | |
| Methoxymethane SCHEMBL9852502 | 0.81 | BCL2 (0.86) | BCL2MCL1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7658937-B2 | Anthraquinones and process for the preparation and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2010-02-09 | — | — | US | claimed |
| CN-101426506-A | Novel anthraquinones and process for the preparation and method of use thereof | UNIV MICHIGAN (US) | 2009-05-06 | — | — | CN | claimed |
| US-20050267307-A1 | Novel anthraquinones and process for the preparation and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2005-12-01 | — | — | US | claimed |
| CN-110522808-A | A kind of anti-treating caput femoris necrosis Chinese medicine composition and preparation method thereof | YIWU LINGCHUAN TECH CO LTD | 2019-12-03 | — | — | CN | disclosed |
| CN-108295591-A | Pollution cleanup composition based on plant extracts | 国润生物科技（深圳）有限公司 | 2018-07-20 | — | — | CN | disclosed |
| CN-108261861-A | Clarifying smoke composition | 国润生物科技（深圳）有限公司 | 2018-07-10 | — | — | CN | disclosed |
| CN-107397967-A | Can effectively solve the air purifying preparation of parking facility air pollutants | 王婧宁 | 2017-11-28 | — | — | CN | disclosed |
| CN-107297128-A | Can the new decorating house of fast purification air freshener | 王婧宁 | 2017-10-27 | — | — | CN | disclosed |
| CN-106943228-A | Traditional Chinese medicine physiotherapy waist support waistband | 彭锐 | 2017-07-14 | — | — | CN | disclosed |
| CN-104688927-A | Paste formula for invigorating kidney and nourishing essence | Xintai hospital of traditional chinese medicine | 2015-06-10 | — | — | CN | disclosed |
| CN-104304539-A | Cancer-eliminating tea containing flavonoid compounds and preparation method thereof | ZHOU JICHUN | 2015-01-28 | — | — | CN | disclosed |
| CN-104138496-A | Pills for treating dysuria of the old | SHANGHAI PUDONG GAOXING BIOTECHNOLOGY RES INST | 2014-11-12 | — | — | CN | disclosed |
| US-7658937-B2 | Anthraquinones and process for the preparation and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2010-02-09 | — | — | US | disclosed |
| US-7658937-B2 | Anthraquinones and process for the preparation and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2010-02-09 | — | — | US | disclosed |
| CN-101426506-A | Novel anthraquinones and process for the preparation and method of use thereof | UNIV MICHIGAN (US) | 2009-05-06 | — | — | CN | disclosed |
| CN-101356996-A | Preparation method of water extract of morinda root and use thereof in cigarette | LONGYAN TOBACCO INDUSTRY CO LT (CN) | 2009-02-04 | — | — | CN | disclosed |
| CN-101356997-A | Preparation method of alcohol extract of morinda root and use thereof in cigarette | LONGYAN TOBACCO INDUSTRY CO LT (CN) | 2009-02-04 | — | — | CN | disclosed |
| EP-1745000-A2 | NOVEL ANTHRAQUINONES AND PROCESS FOR THE PREPARATION AND METHOD OF USE THEREOF | Michigan State University (US) | 2007-01-24 | — | — | EP | disclosed |
| US-20050267307-A1 | Novel anthraquinones and process for the preparation and method of use thereof | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2005-12-01 | — | — | US | disclosed |
| WO-2005113478-A2 | NOVEL ANTHRAQUINONES AND PROCESS FOR THE PREPARATION AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2005-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267307-A1 | Novel anthraquinones and process for the preparation and method of use thereof | PAH, APEH, SDHA | BCL2 2400/4885MCL1 1804/4885MAPT 3904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.