SCHEMBL31748482

SCHEMBL31748482

O=C(Nc1ccc2nc(-c3ccc(F)cc3)[nH]c2c1)c1ccccc1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MMP2 P08253 4/20 0.72
▸ MMP9 P14780 4/20 0.72
▸ MMP8 P22894 4/20 0.72
▸ MMP13 P45452 4/20 0.72
▸ NR2E3 Q9Y5X4 3/20 0.72
▸ CHEK2 O96017 1/20 0.65
▸ HPSE Q9Y251 1/20 0.65
▸ MAPT P10636 5/20 0.63
▸ KMT2A Q03164 2/20 0.63
▸ CYP2C9 P11712 1/20 0.63
▸ CYP2C19 P33261 1/20 0.63
▸ MAPK1 P28482 1/20 0.63
▸ COMT P21964 1/20 0.63
▸ NR4A2 P43354 1/20 0.62
▸ KDR P35968 1/20 0.62
▸ SMN1; SMN2 Q16637 3/20 0.61
▸ RAB9A P51151 2/20 0.61
▸ KDM4E B2RXH2 2/20 0.61
▸ ALDH1A1 P00352 2/20 0.61
▸ POLB P06746 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26597194 1.00 MMP2 (0.72) MMP2MMP9MMP8MMP13NR2E3
SCHEMBL26597177 0.92 MMP2 (0.76) MMP2MMP9MMP8MMP13NR2E3
SCHEMBL30667671 0.92 MMP2 (0.76) MMP2MMP9MMP8MMP13NR2E3
Hydrochloric Acid SCHEMBL19149753 0.90 MMP2 (0.74) MMP2MMP9MMP8MMP13NR2E3
SCHEMBL31748726 0.89 MMP2 (0.70) MMP2MMP9MMP8MMP13NR2E3
SCHEMBL26597181 0.89 MMP2 (0.70) MMP2MMP9MMP8MMP13NR2E3
SCHEMBL14381521 0.86 MMP2 (0.71) MMP2MMP9MMP8MMP13NR2E3
SCHEMBL6128131 0.86 HPSE (0.65) MMP2MMP9MMP8MMP13NR2E3
SCHEMBL27202512 0.86 HPSE (0.88) MMP2MMP9MMP8MMP13HPSE
SCHEMBL14381554 0.84 HPSE (0.69) MMP2MMP9MMP8MMP13NR2E3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388551-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS UNIV PARIS CITE (FR) 2025-12-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388551-A1 COMPOUNDS INDUCING PRODUCTION OF PROTEINS BY IMMUNE CELLS CXCL10, CCR10, IL2 MMP2 2376/4885MMP9 2121/4885MMP8 343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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