SCHEMBL317494

SCHEMBL317494

C=C(CCCN1CCOC1)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.43
HSD17B10 Q99714 1/20 0.38
PAOX Q6QHF9 1/20 0.37
SMN1; SMN2 Q16637 5/20 0.37
CYP1A2 P05177 1/20 0.37
MAPK1 P28482 1/20 0.37
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 4/20 0.37
MAPT P10636 2/20 0.36
KMT2A Q03164 2/20 0.36
GAA P10253 1/20 0.36
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36
TP53 P04637 1/20 0.36
LMNA P02545 2/20 0.36
KEAP1 Q14145 1/20 0.35
TBXAS1 P24557 1/20 0.35
USP2 O75604 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8937751 0.90 GLA (0.50) GLAHSD17B10SMN1; SMN2ALDH1A1KDM4E
SCHEMBL39610 0.90 GLA (0.55) GLAHSD17B10PAOXSMN1; SMN2CYP1A2
SCHEMBL504157 0.80 SMN1; SMN2 (0.50) GLAPAOXSMN1; SMN2CYP1A2MAPK1
SCHEMBL547366 0.79 GLA (0.63) GLAHSD17B10SMN1; SMN2ALDH1A1KDM4E
SCHEMBL7868634 0.78 KDM4E (0.48) GLASMN1; SMN2ALDH1A1KDM4EKMT2A
SCHEMBL8600884 0.78 GLA (0.43) GLAPAOXSMN1; SMN2CYP1A2ALDH1A1
Hydrochloric Acid SCHEMBL11421103 0.77 GLA (0.67) GLAHSD17B10SMN1; SMN2ALDH1A1KDM4E
SCHEMBL1275571 0.77 SMN1; SMN2 (0.62) SMN1; SMN2CYP1A2MAPK1ALDH1A1KDM4E
SCHEMBL489032 0.75 SMN1; SMN2 (0.66) SMN1; SMN2CYP1A2MAPK1ALDH1A1KDM4E
SCHEMBL19412256 0.75 SMN1; SMN2 (0.66) SMN1; SMN2CYP1A2MAPK1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8822585-B2 Aqueous dispersion of polymeric particles ROHM AND HAAS COMPANY (US) 2014-09-02 US disclosed
EP-2324069-B1 MONOMER MIXTURE, POLYMER, COATING MEANS AND METHOD FOR PRODUCING A COATING EVONIK ROEHM GMBH (DE) 2013-12-18 EP disclosed
US-8236431-B2 Cellulosic fiber pulp, filler and hollow-core binders in layers of the paper laminate; binder of a first polymer encapsulated by a second polymer, from ethylenically unsaturated monomers; glossy, bright and smooth paperboard coatings, reducing the amount of binder and opacifying pigment necessary ROHM AND HAAS COMPANY (US) 2012-08-07 US disclosed
WO-2012038197-A1 COATING AGENT HAVING (METH)ACRYLIC POLYMERS AND COALESCENCE ADDITIVES EVONIK RÖHM GMBH (DE) 2012-03-29 WO disclosed
WO-2012004160-A1 COMPOSITION FOR PRODUCING POLYMERS, (METH)ACRYLIC POLYMER, COATING AGENT, AND COATING EVONIK RÖHM GMBH (DE) 2012-01-12 WO disclosed
US-20110160328-A1 PROCESS FOR MAKING UNIFORM POLYMER BEADS ROHM AND HAAS COMPANY 2011-06-30 US disclosed
EP-2324069-A1 MONOMER MIXTURE, POLYMER, COATING MEANS AND METHOD FOR PRODUCING A COATING Evonik Röhm GmbH (DE) 2011-05-25 EP disclosed
US-7939572-B2 Aqueous dispersion of polymeric particles ROHM AND HAAS COMPANY (US) 2011-05-10 US disclosed
US-20100113646-A1 Aqueous dispersion of polymeric particles ROHM AND HAAS COMPANY 2010-05-06 US disclosed
US-7691942-B2 Aqueous dispersion of polymeric particles ROHM AND HAAS COMPANY (US) 2010-04-06 US disclosed
US-7645815-B2 Fast-drying aqueous compositions with hollow particle binders and traffic paints made therewith ROHM AND HAAS COMPANY (US) 2010-01-12 US disclosed
US-20090176127-A1 Fast dry, shelf stable aqueous coating composition comprising a phosphorus acid polymer ROHM AND HAAS COMPANY 2009-07-09 US disclosed
US-20080171810-A1 Fast-drying aqueous compositions with hollow particle binders and traffic paints made therewith ROHM AND HAAS COMPANY 2008-07-17 US disclosed
US-20080081175-A1 Hollow organic pigment core binder coated paper and paperboard articles and methods for making the same ROHM AND HAAS COMPANY 2008-04-03 US disclosed
US-20080058457-A1 Aqueous dispersion of polymeric particles ROHM AND HAAS COMPANY 2008-03-06 US disclosed
US-20070255000-A1 Aqueous dispersion of polymeric particles ROHM AND HAAS COMPANY 2007-11-01 US disclosed
US-20070043159-A1 Aqueous dispersion of polymeric particles ROHM AND HAAS COMPANY 2007-02-22 US disclosed
US-20050203211-A1 Aqueous dispersion of polymeric particles GEBHARD MATTHEW S (US) 2005-09-15 US disclosed
US-20040220329-A1 Aqueous polymer composition and coating produced therefrom SOLOMON ROBERT DAVID (US) 2004-11-04 US disclosed
US-20040102568-A1 Aqueous coating composition BRIDGEWATER BRIAN MICHAEL (US) 2004-05-27 US disclosed