SCHEMBL8937751

SCHEMBL8937751

C=C(CCN1CCOC1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.50
ALDH1A1 P00352 5/20 0.41
MAPT P10636 4/20 0.41
KMT2A Q03164 4/20 0.41
HSD17B10 Q99714 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 2/20 0.39
CYP2C19 P33261 1/20 0.39
HSP90AA1 P07900 1/20 0.36
KDM4E B2RXH2 2/20 0.36
MPI P34949 1/20 0.36
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL317494 0.90 GLA (0.43) GLAALDH1A1MAPTKMT2AHSD17B10
SCHEMBL547366 0.89 GLA (0.63) GLAALDH1A1MAPTKMT2AHSD17B10
Hydrochloric Acid SCHEMBL11421103 0.87 GLA (0.67) GLAALDH1A1MAPTKMT2AHSD17B10
SCHEMBL4789962 0.81 GLA (0.74) GLAALDH1A1MAPTKMT2AHSD17B10
SCHEMBL39610 0.79 GLA (0.55) GLAALDH1A1MAPTKMT2AHSD17B10
SCHEMBL6473449 0.78 GLA (0.42) GLAALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL3834185 0.75 ALDH1A1 (0.54) GLAALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL31092972 0.74 GLA (0.57) GLAALDH1A1MAPTKMT2AHSD17B10
SCHEMBL30422696 0.74 GLA (0.45) GLAALDH1A1MAPTKMT2ALMNA
SCHEMBL5678574 0.73 ALDH1A1 (0.57) ALDH1A1MAPTKMT2ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5499128-A Liquid crystal display device with acrylic polymer spacers and method of manufacturing the same KABUSHIKI KAISHA TOSHIBA (JP) 1996-03-12 US disclosed