SCHEMBL317495

SCHEMBL317495

CC(=CCCN1CCOC1)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.40
HSD17B10 Q99714 2/20 0.38
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 5/20 0.36
SMN1; SMN2 Q16637 2/20 0.34
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
PAOX Q6QHF9 1/20 0.34
CD81 P60033 1/20 0.34
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL317493 1.00 GLA (0.40) GLAHSD17B10ALDH1A1KDM4ESMN1; SMN2
SCHEMBL887123 0.92 GLA (0.49) GLAHSD17B10ALDH1A1KDM4ESMN1; SMN2
SCHEMBL39611 0.92 GLA (0.49) GLAHSD17B10ALDH1A1KDM4ESMN1; SMN2
SCHEMBL8600889 0.86 GLA (0.44) GLAHSD17B10ALDH1A1KDM4ESMN1; SMN2
SCHEMBL5682570 0.82 CD81 (0.39) HSD17B10ALDH1A1PAOXCD81TSHR
SCHEMBL504158 0.82 CD81 (0.39) HSD17B10ALDH1A1PAOXCD81TSHR
SCHEMBL1275573 0.79 CYP1A2 (0.41) HSD17B10ALDH1A1KDM4ESMN1; SMN2CD81
SCHEMBL1275570 0.79 CYP1A2 (0.41) HSD17B10ALDH1A1KDM4ESMN1; SMN2CD81
SCHEMBL715556 0.77 HSD17B10 (0.46) GLAHSD17B10ALDH1A1KDM4ESMN1; SMN2
SCHEMBL489033 0.77 CYP1A2 (0.44) HSD17B10ALDH1A1KDM4ESMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8822585-B2 Aqueous dispersion of polymeric particles ROHM AND HAAS COMPANY (US) 2014-09-02 US disclosed
EP-2324069-B1 MONOMER MIXTURE, POLYMER, COATING MEANS AND METHOD FOR PRODUCING A COATING EVONIK ROEHM GMBH (DE) 2013-12-18 EP disclosed
US-8236431-B2 Cellulosic fiber pulp, filler and hollow-core binders in layers of the paper laminate; binder of a first polymer encapsulated by a second polymer, from ethylenically unsaturated monomers; glossy, bright and smooth paperboard coatings, reducing the amount of binder and opacifying pigment necessary ROHM AND HAAS COMPANY (US) 2012-08-07 US disclosed
WO-2012038197-A1 COATING AGENT HAVING (METH)ACRYLIC POLYMERS AND COALESCENCE ADDITIVES EVONIK RÖHM GMBH (DE) 2012-03-29 WO disclosed
WO-2012004160-A1 COMPOSITION FOR PRODUCING POLYMERS, (METH)ACRYLIC POLYMER, COATING AGENT, AND COATING EVONIK RÖHM GMBH (DE) 2012-01-12 WO disclosed
US-20110160328-A1 PROCESS FOR MAKING UNIFORM POLYMER BEADS ROHM AND HAAS COMPANY 2011-06-30 US disclosed
EP-2324069-A1 MONOMER MIXTURE, POLYMER, COATING MEANS AND METHOD FOR PRODUCING A COATING Evonik Röhm GmbH (DE) 2011-05-25 EP disclosed
US-7939572-B2 Aqueous dispersion of polymeric particles ROHM AND HAAS COMPANY (US) 2011-05-10 US disclosed
US-20100113646-A1 Aqueous dispersion of polymeric particles ROHM AND HAAS COMPANY 2010-05-06 US disclosed
US-7691942-B2 Aqueous dispersion of polymeric particles ROHM AND HAAS COMPANY (US) 2010-04-06 US disclosed
US-7645815-B2 Fast-drying aqueous compositions with hollow particle binders and traffic paints made therewith ROHM AND HAAS COMPANY (US) 2010-01-12 US disclosed
US-20090176127-A1 Fast dry, shelf stable aqueous coating composition comprising a phosphorus acid polymer ROHM AND HAAS COMPANY 2009-07-09 US disclosed
US-20080171810-A1 Fast-drying aqueous compositions with hollow particle binders and traffic paints made therewith ROHM AND HAAS COMPANY 2008-07-17 US disclosed
US-20080081175-A1 Hollow organic pigment core binder coated paper and paperboard articles and methods for making the same ROHM AND HAAS COMPANY 2008-04-03 US disclosed
US-20080058457-A1 Aqueous dispersion of polymeric particles ROHM AND HAAS COMPANY 2008-03-06 US disclosed
US-20070255000-A1 Aqueous dispersion of polymeric particles ROHM AND HAAS COMPANY 2007-11-01 US disclosed
US-20070043159-A1 Aqueous dispersion of polymeric particles ROHM AND HAAS COMPANY 2007-02-22 US disclosed
US-20050203211-A1 Aqueous dispersion of polymeric particles GEBHARD MATTHEW S (US) 2005-09-15 US disclosed
US-20040220329-A1 Aqueous polymer composition and coating produced therefrom SOLOMON ROBERT DAVID (US) 2004-11-04 US disclosed
US-20040102568-A1 Aqueous coating composition BRIDGEWATER BRIAN MICHAEL (US) 2004-05-27 US disclosed