SCHEMBL504158

SCHEMBL504158

CC(=CCCN1CC1)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CD81 P60033 2/20 0.39
PAOX Q6QHF9 1/20 0.36
SIGMAR1 Q99720 3/20 0.36
NPSR1 Q6W5P4 1/20 0.34
SLC6A1 P30531 3/20 0.34
ALDH1A1 P00352 2/20 0.34
LMNA P02545 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
CYP2C19 P33261 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CHRM2 P08172 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5682570 1.00 CD81 (0.39) CD81PAOXSIGMAR1NPSR1SLC6A1
SCHEMBL1275570 0.92 CYP1A2 (0.41) CD81SLC6A1ALDH1A1LMNACYP1A2
SCHEMBL1275573 0.92 CYP1A2 (0.41) CD81SLC6A1ALDH1A1LMNACYP1A2
SCHEMBL489033 0.90 CYP1A2 (0.44) SLC6A1ALDH1A1LMNACYP1A2CYP2D6
SCHEMBL1285651 0.88 PAOX (0.42) CD81PAOXSIGMAR1ALDH1A1CYP1A2
SCHEMBL11444496 0.87 MEN1 (0.40) ALDH1A1LMNACHRM3RAB9A
SCHEMBL39611 0.87 GLA (0.49) PAOXALDH1A1HSD17B10RAB9A
SCHEMBL887123 0.87 GLA (0.49) PAOXALDH1A1HSD17B10RAB9A
SCHEMBL1285998 0.86 PAOX (0.44) CD81PAOXSIGMAR1ALDH1A1CYP1A2
SCHEMBL1286052 0.85 PAOX (0.47) CD81PAOXALDH1A1CYP1A2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3976362-B1 METHOD FOR MAKING OPAQUE COLORED SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2023-06-07 EP claimed
EP-2625217-B1 CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS NOVARTIS AG (CH) 2018-07-04 EP claimed
US-20120088844-A1 CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS ALCON INC. (CH) 2012-04-12 US claimed
US-20120088861-A1 WATER-PROCESSABLE SILICONE-CONTAINING PREPOLYMERS AND USES THEREOF ALCON INC. (CH) 2012-04-12 US claimed
US-5534579-A PAINTS, ACRYLIC MONOMER CONTAINING PIPERIDINE GROUP, CARBOXYLIC ACID CONTAINING EMULSIFIER, REACTION BETWEEN EMULSIFIER AND EMULSION POLYMER NIPPON SHOKUBAI CO., LTD. (JP) 1996-07-09 US claimed
EP-0240439-B1 OLIGOMERS CONTAINING POLYDIENE SEQUENCES AND PHOTOCROSS-LINKABLE GRAFTED GROUPS, AND THEIR USES, ESPECIALLY IN THE COATING OF METALS ELF ATOCHEM S.A. (FR) 1990-08-01 EP claimed
EP-0138934-B1 ACRYLIC TELOMERS WITH PHOTOCROSSLINKABLE GRAFTS, SYNTHESIS THEREOF AND THEIR APPLICATIONS TO THE COATING OF METALS Société Anonyme dite: NORSOLOR (FR) 1989-03-15 EP claimed
EP-0186427-B1 STRETCHED SURFACE RECORDING MEDIUM MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-02-01 EP claimed
US-3993716-A FREE RADICAL SOLUTION POLYMERIZATION, RING OPENING, GRAFT POLYMERIZATION, VINYL MONOMERS, STABILIZED COATINGS DOW BADISCHE COMPANY (US) 1976-11-23 US claimed
WO-2023171516-A1 SHEET FOR WORKPIECE PROCESSING AND MANUFACTURING METHOD OF PROCESSED WORKPIECE リンテック株式会社 2023-09-14 WO disclosed
WO-2023171079-A1 SHEET FOR WORKPIECE PROCESSING AND MANUFACTURING METHOD OF PROCESSED WORKPIECE リンテック株式会社 2023-09-14 WO disclosed
WO-2023171515-A1 SHEET FOR WORKPIECE PROCESSING AND MANUFACTURING METHOD OF PROCESSED WORKPIECE リンテック株式会社 2023-09-14 WO disclosed
US-20210292536-A1 RESIN COMPOSITION, ADHESIVE MEMBER, AND DISPLAY DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-09-23 US disclosed
EP-3835368-A1 AQUEOUS DISPERSION, PRODUCTION METHOD THEREFOR, COATING COMPOSITION, AND COATING FILM Nippon Shokubai Co., Ltd. (JP) 2021-06-16 EP disclosed
US-4634633-A THERMOPLASTIC POLYURETHANE-UREA SONY CORPORATION (JP) 1987-01-06 US disclosed
US-4623570-A Stable stretched surface recording medium MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-11-18 US disclosed
EP-0146897-A2 Magnetic recording medium SONY CORPORATION (JP) 1985-07-03 EP disclosed
US-4026880-A Silanes having an amine functional group thereon GENERAL ELECTRIC COMPANY (US) 1977-05-31 US disclosed
US-3993716-A FREE RADICAL SOLUTION POLYMERIZATION, RING OPENING, GRAFT POLYMERIZATION, VINYL MONOMERS, STABILIZED COATINGS DOW BADISCHE COMPANY (US) 1976-11-23 US disclosed
US-3993716-A FREE RADICAL SOLUTION POLYMERIZATION, RING OPENING, GRAFT POLYMERIZATION, VINYL MONOMERS, STABILIZED COATINGS DOW BADISCHE COMPANY (US) 1976-11-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088844-A1 CHAIN-EXTENDED POLYSILOXANE CROSSLINKERS WITH DANGLING HYDROPHILIC POLYMER CHAINS HACD2, HACD3, PCNA CD81 2441/4885PAOX 287/4885SIGMAR1 1188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.