Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | MGAM | O43451 | 4/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.47 |
| ▸ | SI | P14410 | 4/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.47 |
| ▸ | XPO1 | O14980 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31749889 | 0.90 | GAA (0.59) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL31749467 | 0.87 | MGAM (0.42) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL31749736 | 0.87 | ELANE (0.48) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL31749573 | 0.80 | MAPT (0.35) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL31749808 | 0.79 | MGAM (0.50) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL31749531 | 0.77 | MGAM (0.53) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL31749811 | 0.76 | MGAM (0.44) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL31749637 | 0.75 | MGAM (0.50) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL31749631 | 0.75 | MGAM (0.45) | GAAMGAMAMY1ASIMGAM2 | |
| SCHEMBL11631222 | 0.71 | PARP1 (0.51) | GAAXPO1ELANESMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025264724-A1 | MPRO INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-12-26 | — | — | WO | disclosed |