Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 8/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 8/20 | 0.45 |
| ▸ | GAA | P10253 | 8/20 | 0.45 |
| ▸ | SI | P14410 | 8/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 8/20 | 0.45 |
| ▸ | F12 | P00748 | 4/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31749637 | 0.89 | MGAM (0.50) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749893 | 0.88 | MGAM (0.37) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749631 | 0.86 | MGAM (0.45) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749736 | 0.83 | ELANE (0.48) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749664 | 0.82 | MGAM (0.45) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749538 | 0.79 | MGAM (0.42) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749537 | 0.79 | F12 (0.46) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749808 | 0.79 | MGAM (0.50) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749811 | 0.77 | MGAM (0.44) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749531 | 0.77 | MGAM (0.53) | MGAMAMY1AGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025264724-A1 | MPRO INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-12-26 | — | — | WO | disclosed |