SCHEMBL3174994

SCHEMBL3174994

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nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1706477 0.81
SCHEMBL378171 0.81
SCHEMBL28399333 0.76
SCHEMBL17241752 0.74 GRIK1 (0.31)
SCHEMBL387047 0.74 OPRM1 (0.39)
SCHEMBL8171362 0.73
SCHEMBL130677 0.72
SCHEMBL24468 0.67
SCHEMBL22802544 0.65
SCHEMBL964871 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024086810-A1 LYMPHATIC ENDOTHELIAL CELL-SPECIFIC LIPID NANOPARTICLE AND USES THEREOF GEORGIA TECH RESEARCH CORPORATION (US) 2024-04-25 WO disclosed
US-20230373932-A1 DIHYDROPYRIMIDIN-2-ONE COMPOUNDS AND MEDICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2023-11-23 US disclosed
WO-2023192701-A1 MEMBRANES FOR THE SEPARATION OF H2S FROM H2S-CO2 MIXTURES OHIO STATE INNOVATION FOUNDATION (US) 2023-10-05 WO disclosed
US-20210130300-A1 DIHYDROPYRIMIDIN-2-ONE COMPOUNDS AND MEDICAL USE THEREOF JAPAN TOBACCO INC. (JP) 2021-05-06 US disclosed
EP-3744713-A1 DIYHYDROPYRIMIDINE-2-ONE COMPOUNDS AND MEDICINAL USES THEREOF Japan Tobacco Inc. (JP) 2020-12-02 EP disclosed
CN-107949625-B Hydrocarbon soluble/dispersible hemiformals as hydrogen sulfide scavengers 艺康美国股份有限公司 2020-10-02 CN disclosed
CN-107001286-B Dihydropyrimidine-2-one compounds and medicinal use thereof 日本烟草产业株式会社 2020-07-07 CN disclosed
EP-3347441-B1 HYDROCARBON SOLUBLE/DISPERSIBLE HEMIFORMALS AS HYDROGEN SULFIDE SCAVENGERS ECOLAB USA INC (US) 2020-06-10 EP disclosed
EP-3231793-B1 DIHYDROPYRIMIDINE-2-ONE COMPOUNDS AND MEDICINAL USES THEREOF JAPAN TOBACCO INC (JP) 2020-03-11 EP disclosed
EP-3558986-A1 SUBSTITUTED 1,2,4-THIADIAZOLYL PYRROLONES AND 1,2,4-THIADIAZOLYL HYDANTOINES AND SALTS THEREOF AND USE THEREOF AS HERBICIDES Bayer CropScience Aktiengesellschaft (DE) 2019-10-30 EP disclosed
US-5610182-A ADMINISTERING AN ISOCARBACYCLIN OF SPECIFIC STRUCTURE IN THE FORM OF A FAT EMULSION TEIJIN, LIMITED (JP) 1997-03-11 US disclosed
US-5530027-A PROSTAGLANDINS AND/OR ITS OPTICAL ISOMER FOR SKIN DISORDERS TEIJIN LIMITED (JP) 1996-06-25 US disclosed
CN-1101781-A Pharmaceutical composition for treating cerebral thrombosis TEIJIN LTD (JP) 1995-04-19 CN disclosed
EP-0638312-A1 DERMATOLOGIC PREPARATION COMPOSITION CONTAINING ISOCARBACYCLIN AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1995-02-15 EP disclosed
EP-0634172-A1 DERMATOLOGIC PREPARATION COMPOSITION CONTAINING PROSTACYCLIN AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1995-01-18 EP disclosed
EP-0634171-A1 PHARMACEUTICAL COMPOSITION FOR TREATING CEREBRAL THROMBOSIS TEIJIN LIMITED (JP) 1995-01-18 EP disclosed
US-5234946-A Anticholesterol, antilipemic BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-08-10 US disclosed
EP-0318860-B1 SUBSTITUTED ALKYLAMINE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-06-16 EP disclosed
CN-1037141-A The alkylamine derivative that replaces BANYU PHARMA CO LTD (JP) 1989-11-15 CN disclosed
EP-0318860-A2 Substituted alkylamine derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-06-07 EP disclosed