SCHEMBL3175019

SCHEMBL3175019

C=C(Cl)CCCCCCCCC(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.67
LMNA P02545 3/20 0.67
NFKB1 P19838 1/20 0.67
PMP22 Q01453 1/20 0.67
GPR84 Q9NQS5 8/20 0.55
FFAR1 O14842 2/20 0.55
FFAR4 Q5NUL3 2/20 0.55
SLC22A6 Q4U2R8 2/20 0.53
PPARG P37231 7/20 0.52
PPARD Q03181 7/20 0.52
PPARA Q07869 7/20 0.52
HDAC11 Q96DB2 5/20 0.52
ALDH1A1 P00352 3/20 0.52
PTPN1 P18031 3/20 0.52
TLR2 O60603 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
MEN1 O00255 2/20 0.52
FABP4 P15090 2/20 0.52
ALOX15 P16050 2/20 0.52
KMT2A Q03164 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28273706 1.00 TSHR (0.67) TSHRLMNANFKB1PMP22GPR84
SCHEMBL23829936 0.92
SCHEMBL28977802 0.83 TSHR (0.56) TSHRLMNANFKB1PMP22GPR84
SCHEMBL8983651 0.82
Ethylene SCHEMBL7055894 0.82 TSHR (0.86) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL7053993 0.82 TSHR (0.86) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL7056501 0.82 TSHR (0.86) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL7058067 0.82 TSHR (0.86) TSHRLMNANFKB1PMP22GPR84
Ethylene SCHEMBL7053999 0.82 TSHR (0.86) TSHRLMNANFKB1PMP22GPR84
Azelaic Acid SCHEMBL2484376 0.82 TSHR (0.86) TSHRLMNANFKB1PMP22GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220298352-A1 SILICONE COMPOSITION AND METHOD FOR MANUFACTURING COMPOSITE MOLDINGS WACKER CHEMIE AG (DE) 2022-09-22 US disclosed
US-20220228002-A1 SURFACE-COATED INORGANIC PARTICLES AND METHOD FOR MANUFACTURING SAME, AND ORGANIC SOLVENT DISPERSION CONTAINING SAME ISHIHARA SANGYO KAISHA LTD (JP) 2022-07-21 US disclosed
EP-4017921-A1 SILICONE COMPOSITION AND METHOD FOR MANUFACTURING COMPOSITE MOLDINGS Wacker Chemie AG (DE) 2022-06-29 EP disclosed
CN-114080428-A Surface-coated inorganic particles, method for producing same, and organic solvent dispersion containing same 石原产业株式会社 2022-02-22 CN disclosed
WO-2021032275-A1 SILICONE COMPOSITION AND METHOD FOR MANUFACTURING COMPOSITE MOLDINGS WACKER CHEMIE AG (DE) 2021-02-25 WO disclosed
WO-2020255731-A1 SURFACE-COATED INORGANIC PARTICLES AND METHOD FOR MANUFACTURING SAME, AND ORGANIC SOLVENT DISPERSION CONTAINING SAME 石原産業株式会社 2020-12-24 WO disclosed
EP-1817109-B1 MIXED-MODAL ANION-EXCHANGE TYPE SEPARATION MATERIAL MERCK PATENT GMBH (DE) 2020-02-26 EP disclosed
US-7648636-B2 A chromatographic support including an immobilized ligand which combines an anion-exchange domain comprising an oligocyclic aza compound with endocyclic nitrogen and a non-ionic, second binding domain to allow adjustment of the overall hydrophobicity/hydrophilicity; separation; purification; peptides MERCK PATENT GMBH (DE) 2010-01-19 US disclosed
EP-1288230-B1 METHOD OF PURIFYING VINYL POLYMER KANEKA CORP (JP) 2008-10-01 EP disclosed
US-20080164211-A1 Mixed-Modal Anion-Exchanged Type Separation Material MERCK PATENT GMBH (DE) 2008-07-10 US disclosed
US-7141646-B2 Method of purifying vinyl polymer KANEKA CORPORATION (JP) 2006-11-28 US disclosed
EP-1693108-A1 Mixed-modal anion-exchange type separation material MERCK PATENT GmbH (DE) 2006-08-23 EP disclosed
WO-2006058623-A1 MIXED-MODAL ANION-EXCHANGE TYPE SEPARATION MATERIAL MERCK PATENT GMBH (DE) 2006-06-08 WO disclosed
US-20030181634-A1 Method of purifying vinyl polymer KANEKA CORPORATION (JP) 2003-09-25 US disclosed
EP-1288230-A1 METHOD OF PURIFYING VINYL POLYMER KANEKA CORPORATION (JP) 2003-03-05 EP disclosed
EP-0869964-B1 REACTIVE ORGANOSILICON COMPOUNDS DU PONT (US) 2002-12-04 EP disclosed
EP-0869964-A1 REACTIVE ORGANOSILICON COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-10-14 EP disclosed
US-5719251-A Reactive organosilicon compounds E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-02-17 US disclosed
WO-1996027599-A1 REACTIVE ORGANOSILICON COMPOUNDS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-09-12 WO disclosed
US-4803228-A ACNE TREATMENT L'OREAL (FR) 1989-02-07 US disclosed