Azelaic Acid

Azelaic Acid

SCHEMBL2484376

C=C.O=C(O)CCCCCCCC(=O)O

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.86
LMNA P02545 3/20 0.86
NFKB1 P19838 1/20 0.86
PMP22 Q01453 1/20 0.86
GPR84 Q9NQS5 8/20 0.67
FFAR1 O14842 2/20 0.67
FFAR4 Q5NUL3 2/20 0.67
SLC22A6 Q4U2R8 2/20 0.67
PPARG P37231 7/20 0.63
PPARD Q03181 7/20 0.63
PPARA Q07869 7/20 0.63
HDAC11 Q96DB2 5/20 0.63
ALDH1A1 P00352 3/20 0.63
PTPN1 P18031 3/20 0.63
TLR2 O60603 2/20 0.63
TDP1 Q9NUW8 2/20 0.63
MEN1 O00255 2/20 0.63
FABP4 P15090 2/20 0.63
ALOX15 P16050 2/20 0.63
KMT2A Q03164 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL7059164 1.00 TSHR (0.86) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL7053731 1.00 TSHR (0.86) TSHRLMNANFKB1PMP22GPR84
Ethylene SCHEMBL7053999 1.00 TSHR (0.86) TSHRLMNANFKB1PMP22GPR84
Ethylene SCHEMBL7053736 1.00 TSHR (0.86) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL7058067 1.00 TSHR (0.86) TSHRLMNANFKB1PMP22GPR84
Ethylene SCHEMBL873940 1.00 TSHR (0.86) TSHRLMNANFKB1PMP22GPR84
Ethylene SCHEMBL7060522 1.00 TSHR (0.86) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL7056501 1.00 TSHR (0.86) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL586054 1.00 TSHR (0.86) TSHRLMNANFKB1PMP22GPR84
Sebacic Acid SCHEMBL7053993 1.00 TSHR (0.86) TSHRLMNANFKB1PMP22GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4029637-A FIBERS AKZONA INCORPORATED (US) 1977-06-14 US claimed
US-12558274-B2 Absorbent cores having material free areas THE PROCTER & GAMBLE COMPANY (US) 2026-02-24 US disclosed
US-20260026982-A1 ABSORBENT CORE WITH PROFILED DISTRIBUTION OF ABSORBENT MATERIAL PROCTER & GAMBLE (US) 2026-01-29 US disclosed
US-12472111-B2 Absorbent core with profiled distribution of absorbent material THE PROCTER & GAMBLE COMPANY (US) 2025-11-18 US disclosed
US-20250312203-A1 ABSORBENT ARTICLES WITH CHANNELS AND/OR POCKETS PROCTER & GAMBLE (US) 2025-10-09 US disclosed
US-20250213401-A1 ABSORBENT ARTICLE WITH A DISTRIBUTION LAYER COMPRISING CHANNELS PROCTER & GAMBLE (US) 2025-07-03 US disclosed
US-20250205094-A1 ABSORBENT ARTICLE WITH HIGH ABSORBENT MATERIAL CONTENT PROCTER & GAMBLE (US) 2025-06-26 US disclosed
US-20250188501-A1 SEMISYNTHETIC ROUTES TO ORGANIC COMPOUNDS AGAIN BIO APS (DK) 2025-06-12 US disclosed
US-20250143934-A1 ABSORBENT ARTICLES HAVING CHANNEL-FORMING AREAS AND WETNESS INDICATOR PROCTER & GAMBLE (US) 2025-05-08 US disclosed
US-12279941-B2 Absorbent article with a distribution layer comprising channels THE PROCTER & GAMBLE COMPANY (US) 2025-04-22 US disclosed
US-4424244-A SARAN, VINYL ACETATE-VINYL ALCOHOL-COPOLYMER OR TERPOLYMER, POLYESTER, BLOCK POLYMER PERMACEL (US) 1984-01-03 US disclosed
US-4393223-A THERMAL DEPOLYMERIZATION OF POLYESTERS EMERY INDUSTRIES, INC. (US) 1983-07-12 US disclosed
US-4379806-A BLOCK POLYMER, TACKIFIER RESIN, COEXTRUSION, BACKINGS JOHNSON & JOHNSON (US) 1983-04-12 US disclosed
US-4350808-A Copolyester compositions EASTMAN KODAK COMPANY (US) 1982-09-21 US disclosed
US-4331603-A Process for improving the fragrance properties of macrocyclic compounds obtained by thermal depolymerization EMERY INDUSTRIES, INC. (US) 1982-05-25 US disclosed
US-4218379-A Process for the production of macrocyclic esters EMERY INDUSTRIES, INC. (US) 1980-08-19 US disclosed
US-4196254-A Pressure-sensitive adhesive tape with primer JOHNSON & JOHNSON (US) 1980-04-01 US disclosed
US-4165321-A Process for the production of heterocyclic compounds HENKEL CORPORATION, A DE CORP. 1979-08-21 US disclosed
US-4029637-A FIBERS AKZONA INCORPORATED (US) 1977-06-14 US disclosed
US-4029637-A FIBERS AKZONA INCORPORATED (US) 1977-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12558274-B2 Absorbent cores having material free areas DSG1, CUTA, USP10 TSHR 3520/4885LMNA 2049/4885NFKB1 1921/4885
US-20260026982-A1 ABSORBENT CORE WITH PROFILED DISTRIBUTION OF ABSORBENT MATERIAL CUTA, DSP, GJA1 TSHR 4659/4885LMNA 330/4885NFKB1 2575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.