Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31750637 | 0.84 | CYP1A2 (0.54) | KDM4EALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL31750694 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL18336768 | 0.79 | KDM4E (0.39) | KDM4EALDH1A1MAPTPOLBHTT | |
| SCHEMBL31750717 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1MAPTPOLBHTT | |
| SCHEMBL31750804 | 0.77 | POLB (0.49) | KDM4EALDH1A1POLBSMN1; SMN2CASP3 | |
| SCHEMBL31752292 | 0.76 | KDM4E (0.43) | KDM4EALDH1A1MAPTPOLBHTT | |
| SCHEMBL10085577 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1MAPTPOLBSMN1; SMN2 | |
| SCHEMBL18337338 | 0.75 | AADAT (0.45) | POLBHTTSMN1; SMN2RAB9AKMT2A | |
| SCHEMBL31750552 | 0.74 | KDM4E (0.47) | KDM4EALDH1A1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL31750690 | 0.74 | CYP1A2 (0.68) | KDM4EALDH1A1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025264954-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2025-12-26 | — | — | WO | disclosed |