SCHEMBL3175199

SCHEMBL3175199

O=C(O)CCCOc1cccc(F)c1

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 8/20 0.66
FFAR1 O14842 6/20 0.66
CYSLTR2 Q9NS75 1/20 0.51
CYSLTR1 Q9Y271 1/20 0.51
NR4A2 P43354 1/20 0.49
PDK2 Q15119 1/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
KMT2A Q03164 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1008501 0.94 FFAR1 (0.60) FFAR4FFAR1CYSLTR2CYSLTR1NR4A2
SCHEMBL1889231 0.92 FFAR1 (0.56) FFAR4FFAR1NR4A2PDK2MEN1
SCHEMBL29757228 0.92 FFAR1 (0.56) FFAR4FFAR1NR4A2PDK2MEN1
SCHEMBL15546230 0.85 FFAR1 (0.52) FFAR4FFAR1NR4A2MEN1ALDH1A1
SCHEMBL13527394 0.85 FFAR1 (0.51) FFAR4FFAR1NR4A2
SCHEMBL6328915 0.83 MRGPRX4 (0.52) FFAR4FFAR1MEN1ALDH1A1HPGD
SCHEMBL28543877 0.82 FFAR4 (0.50) FFAR4FFAR1PDK2
SCHEMBL3947131 0.81 CNR2 (0.58) FFAR4FFAR1CYSLTR2CYSLTR1
SCHEMBL30639265 0.81 PPARA (0.58) FFAR4FFAR1CYSLTR2CYSLTR1
SCHEMBL1431527 0.81 LMNA (0.64) FFAR1NR4A2MEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040067576-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2004-04-08 US claimed
US-20030208029-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2003-11-06 US claimed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US claimed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP claimed
CN-112624997-A Preparation method and application of 3-amino-2-oxazolidinone derivatives 中国人民解放军军事科学院军事医学研究院 2021-04-09 CN disclosed
US-RE48164-E1 Compounds and compositions for delivering active agents EMISPHERE TECHNOLOGIES INC. (US) 2020-08-18 US disclosed
US-RE48164-E1 Compounds and compositions for delivering active agents EMISPHERE TECHNOLOGIES INC. (US) 2020-08-18 US disclosed
EP-2875001-B1 NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS SUNSHINE LAKE PHARMA CO LTD (CN) 2019-01-09 EP disclosed
EP-2057112-B1 COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS EMISPHERE TECH INC (US) 2018-12-19 EP disclosed
US-9434695-B2 Nitrogenous heterocyclic derivatives and their application in drugs SUNSHINE LAKE PHARMA CO., LTD (CN) 2016-09-06 US disclosed
CN-103570630-B Nitrogen heterocyclic derivative and the application in medicine thereof SUNSHINE LAKE PHARMA CO.,LTD. (CN) 2016-04-20 CN disclosed
EP-2875001-A1 NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS Sunshine Lake Pharma Co., Ltd. (CN) 2015-05-27 EP disclosed
US-6649381-B1 Biosynthesis of high purity polylactones CANON KABUSHIKI KAISHA (JP) 2003-11-18 US disclosed
US-20030208029-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2003-11-06 US disclosed
US-6586562-B2 Polylactone with units such as of 3-hydroxy-5-(4-fluorophenyl)valeric acid; biosynthesis of the polylactone by microorganism; Pseudomonas cichorii; P. putida; P. jessenii CANON KABUSHIKI KAISHA (JP) 2003-07-01 US disclosed
US-20020022253-A1 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2002-02-21 US disclosed
CN-1321695-A Poly(hydroxy alkanoate), its preparation method and use of microbe in its preparation CANON KK (JP) 2001-11-14 CN disclosed
EP-1113033-A2 Polyhydroxyalkanoate, method for production thereof and microorganisms for use in the same CANON KABUSHIKI KAISHA (JP) 2001-07-04 EP disclosed
US-5521147-A HERBICIDES FMC CORPORATION (US) 1996-05-28 US disclosed
EP-0400403-A2 N-aryl-nitrogen-heterocycles BAYER AG (DE) 1990-12-05 EP disclosed