Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | USP1 | O94782 | 4/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | CFB | P00751 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31751975 | 1.00 | LTA4H (0.34) | LTA4HRORCUSP1GPBAR1NPC1 | |
| SCHEMBL31753319 | 1.00 | LTA4H (0.34) | LTA4HRORCUSP1GPBAR1NPC1 | |
| SCHEMBL31751624 | 0.91 | PIK3C3 (0.35) | LTA4HUSP1CYP2A13CD274GSK3B | |
| SCHEMBL31751599 | 0.91 | PIK3C3 (0.35) | LTA4HUSP1CYP2A13CD274GSK3B | |
| SCHEMBL31752996 | 0.91 | PIK3C3 (0.35) | LTA4HUSP1CYP2A13CD274GSK3B | |
| SCHEMBL31752464 | 0.89 | MEN1 (0.37) | LTA4HUSP1CYP2A13GSK3BCFB | |
| SCHEMBL31753002 | 0.89 | MEN1 (0.37) | LTA4HUSP1CYP2A13GSK3BCFB | |
| SCHEMBL31753444 | 0.89 | MEN1 (0.37) | LTA4HUSP1CYP2A13GSK3BCFB | |
| SCHEMBL31751587 | 0.85 | KMT2A (0.42) | CFBALDH1A1MEN1KMT2A | |
| SCHEMBL31753110 | 0.85 | KMT2A (0.42) | CFBALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025264672-A1 | INHIBITORS OF MOBILIZED COLISTIN RESISTANCE ENZYME (MCR-1) AND METHODS OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2025-12-26 | — | — | WO | claimed |
| WO-2025264672-A1 | INHIBITORS OF MOBILIZED COLISTIN RESISTANCE ENZYME (MCR-1) AND METHODS OF USE THEREOF | BAYLOR COLLEGE OF MEDICINE (US) | 2025-12-26 | — | — | WO | disclosed |