SCHEMBL3175352

SCHEMBL3175352

O=C(O)CCCCCCCCCC(C(=O)O)(c1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.50
HDAC4 P56524 2/20 0.50
HDAC1 Q13547 2/20 0.50
HDAC7 Q8WUI4 2/20 0.50
HDAC2 Q92769 2/20 0.50
HDAC10 Q969S8 2/20 0.50
HDAC11 Q96DB2 2/20 0.50
HDAC8 Q9BY41 2/20 0.50
HDAC6 Q9UBN7 2/20 0.50
HDAC9 Q9UKV0 2/20 0.50
HDAC5 Q9UQL6 2/20 0.50
MAPT P10636 2/20 0.50
RXFP1 Q9HBX9 1/20 0.50
NPSR1 Q6W5P4 1/20 0.45
MAPK1 P28482 1/20 0.44
ADRA1A P35348 1/20 0.44
SLC6A3 Q01959 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
LMNA P02545 3/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20564310 1.00 HDAC3 (0.50) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL3165603 1.00 HDAC3 (0.50) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL7011842 1.00 HDAC3 (0.50) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL7006022 1.00 HDAC3 (0.50) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL10793796 1.00 HDAC3 (0.50) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL7006072 1.00 HDAC3 (0.50) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL20564637 0.98 HDAC3 (0.47) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL523363 0.93 HDAC3 (0.47) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL11745181 0.87 GPR84 (0.46) HDAC11MAPTTSHRALDH1A1TDP1
SCHEMBL4214690 0.86 ESR1 (0.51) HDAC3HDAC4HDAC1HDAC7HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1587681-B1 A FORMABLE THERMOPLASTIC LAMINATE, A FORMED LAMINATE, AN ARTICLE, AND A METHOD OF MAKING AN ARTICLE SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-06-08 EP disclosed
CN-1756660-B A formable thermoplastic laminate, a formed laminate, an article, and a method of making an article SABIC INNOVATIVE PLASTICS IP 2010-10-27 CN disclosed
WO-2010005671-A1 A FORMABLE THERMOPLASTIC MULTI-LAYER ARTICLE, A FORMED MULTI-LAYER ARTICLE, AN ARTICLE, AND A METHOD OF MAKING AN ARTICLE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-01-14 WO disclosed
US-20100009207-A1 FORMABLE THERMOPLASTIC MULTI-LAYER ARTICLE, A FORMED MULTI-LAYER ARTICLE, AN ARTICLE, AND A METHOD OF MAKING AN ARTICLE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-01-14 US disclosed
US-7514147-B2 Formable thermoplastic multi-layer laminate, a formed multi-layer laminate, an article, and a method of making an article SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-04-07 US disclosed
US-7112645-B2 polycarbonate that has low levels of ionic species, unreacted monomers and small molecule side products which can be detrimental to the taste and other organoleptic properties of food and beverages residing in containers made of polycarbonate GENERAL ELECTRIC COMPANY (US) 2006-09-26 US disclosed
CN-1756660-A A formable thermoplastic laminate, a formed laminate, an article, and a method of making an article GEN ELECTRIC (US) 2006-04-05 CN disclosed
EP-1587681-A1 A FORMABLE THERMOPLASTIC LAMINATE, A FORMED LAMINATE, AN ARTICLE, AND A METHOD OF MAKING AN ARTICLE GENERAL ELECTRIC COMPANY (US) 2005-10-26 EP disclosed
WO-2005092951-A1 A POLYCARBONATE COMPOSITION AND METHOD OF MAKING THEREOF GENERAL ELECTRIC COMPANY (A NEW YORK CORPORATION) (US) 2005-10-06 WO disclosed
US-20050209434-A1 polycarbonate that has low levels of ionic species, unreacted monomers and small molecule side products which can be detrimental to the taste and other organoleptic properties of food and beverages residing in containers made of polycarbonate CITIBANK, N.A., AS COLLATERAL AGENT 2005-09-22 US disclosed
EP-0859373-B1 Conductive resin composition RIKEN TECHNOS CORP (JP) 2002-05-15 EP disclosed
EP-1156078-A1 Polycarbonate resin composition for optical use GENERAL ELECTRIC COMPANY (US) 2001-11-21 EP disclosed
US-20010041759-A1 Polycarbonate resin composition for optical use SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2001-11-15 US disclosed
EP-0685526-B1 Fire-resistant polycarbonate resin composition GEN ELECTRIC (US) 2001-08-29 EP disclosed
US-6271290-B1 OPTICAL POLYMERS PREPARED BY MELT CONDENSATION GENERAL ELECTRIC COMPANY 2001-08-07 US disclosed
US-6043310-A FIRE-RESISTANT POLYCARBONATE RESIN COMPOSITION CONTAINING LIQUID CRYSTAL POLYMER, FLAME RETARDANT, POLYTETRAFLUOROETHYLENE. GENERAL ELECTRIC COMPANY (US) 2000-03-28 US disclosed
US-6037395-A BLEND OF POLYESTER CONTAINING CYCLOHEXANEDIMETHANOL/1,4-/ MONOMER, AROMATIC POLYCARBONATE, AND 2-OXAZOLINE COMPOUND; TENSILE AND IMPACT STRENGTH; HEAT RESISTANCE, MOISTURE ABSORPTION RIKEN VINYL INDUSTRY CO., LTD. 2000-03-14 US disclosed
EP-0859373-A1 Conductive resin composition RIKEN VINYL INDUSTRY CO., LTD. (JP) 1998-08-19 EP disclosed
EP-0685526-A2 Fire-resistant polycarbonate resin composition GENERAL ELECTRIC COMPANY (US) 1995-12-06 EP disclosed
EP-0605194-A2 Transparent polycarbonate-polyester-blends GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed