SCHEMBL31753554

SCHEMBL31753554

O=Cc1cc(Br)cnc1[N+](=O)[O-]

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 7/20 0.47
MAPT P10636 3/20 0.39
ALDH1A1 P00352 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
PRKDC P78527 1/20 0.34
HSD17B10 Q99714 1/20 0.34
KMT2A Q03164 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MEN1 O00255 1/20 0.32
HTT P42858 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
OPRK1 P41145 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17533491 1.00 ERN1 (0.47) ERN1MAPTALDH1A1KDM4ECYP3A4
SCHEMBL23199502 0.79 ERN1 (0.38) ERN1MAPTALDH1A1KDM4ECYP3A4
SCHEMBL17533404 0.78 MAPT (0.34) ERN1MAPTALDH1A1RAB9AHTT
SCHEMBL31475345 0.77 MAPT (0.47) MAPTALDH1A1KDM4ECYP3A4KMT2A
SCHEMBL29857810 0.74 MAPT (0.41) MAPTALDH1A1KMT2ANPC1RAB9A
SCHEMBL26975272 0.74 MAPT (0.41) MAPTALDH1A1KDM4ECYP3A4HSD17B10
SCHEMBL2586421 0.74 MAPT (0.41) ERN1MAPTALDH1A1KDM4EALOX15
SCHEMBL28760235 0.74 MAPT (0.41) MAPTKDM4EKMT2ANPC1RAB9A
SCHEMBL15616434 0.74 MAPT (0.41) MAPTALDH1A1KMT2ANPC1RAB9A
SCHEMBL899057 0.74 MAPT (0.41) MAPTALDH1A1CYP3A4ALOX15KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108546-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-23 US disclosed
WO-2025264700-A1 GIP RECEPTOR AGONIST COMPOUNDS ELI LILLY AND COMPANY (US) 2025-12-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108546-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GCGR ERN1 3402/4885MAPT 4866/4885ALDH1A1 2982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.