Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.41 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31752430 | 0.84 | CHRNA10 (0.49) | HRH3KDM4ETP53CHRNA10CHRNA9 | |
| SCHEMBL23261764 | 0.81 | HRH3 (0.51) | HRH3KDM4ETP53CHRNA10CHRNA9 | |
| SCHEMBL29148153 | 0.80 | IGF1R (0.38) | HRH3POLB | |
| SCHEMBL30646315 | 0.78 | MAPT (0.43) | KDM4ETP53HTR7POLBGRM2 | |
| SCHEMBL19570981 | 0.75 | HRH3 (0.55) | HRH3KDM4ETP53CHRNA10CHRNA9 | |
| SCHEMBL1481831 | 0.75 | HRH3 (0.55) | HRH3KDM4ETP53CHRNA10CHRNA9 | |
| Hydrochloric Acid SCHEMBL1482412 | 0.73 | HRH3 (0.54) | HRH3KDM4ETP53CHRNA10CHRNA9 | |
| SCHEMBL21891921 | 0.73 | HRH3 (0.54) | HRH3KDM4ETP53CHRNA10CHRNA9 | |
| SCHEMBL24319287 | 0.72 | KDM4E (0.41) | KDM4EPOLB | |
| SCHEMBL31752769 | 0.72 | CHRNA7 (0.43) | HRH3CHRNA10CHRNA9POLBCHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262297-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2025-12-26 | — | — | WO | disclosed |