Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31753473 | 0.92 | NPC1 (0.61) | NPC1RAB9APRMT5WDR77KAT6A | |
| SCHEMBL31753707 | 0.77 | NPC1 (0.61) | NPC1RAB9AHDAC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31753001 | 0.77 | SMN1; SMN2 (0.58) | RAB9APRMT5WDR77KAT6AHDAC3 | |
| SCHEMBL31396764 | 0.76 | KMT2A (0.59) | NPC1RAB9APRMT5WDR77KAT6A | |
| SCHEMBL21218896 | 0.74 | LMNA (0.60) | PRMT5WDR77KAT6AHDAC3HDAC1 | |
| SCHEMBL13010674 | 0.74 | NPC1 (0.57) | NPC1RAB9APRMT5WDR77KAT6A | |
| SCHEMBL13472107 | 0.73 | SMN1; SMN2 (0.54) | NPC1RAB9ACYP17A1LMNAALDH1A1 | |
| SCHEMBL29867230 | 0.73 | CYP1A2 (0.61) | NPC1RAB9AKAT6AHDAC3HDAC1 | |
| SCHEMBL5337975 | 0.73 | CYP1A2 (0.61) | NPC1RAB9AKAT6AHDAC3HDAC1 | |
| SCHEMBL7074306 | 0.73 | NAMPT (0.57) | NPC1RAB9APRMT5WDR77KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025264818-A1 | STAT6 MODULATORS AND METHODS OF USES THEREOF | RAYTHERA, INC. (US) | 2025-12-26 | — | — | WO | disclosed |