Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31756581 | 1.00 | USP30 (0.44) | USP30KEAP1NFE2L2STSACHE | |
| SCHEMBL16633584 | 0.81 | USP30 (0.61) | USP30KEAP1NFE2L2STSACHE | |
| SCHEMBL16633796 | 0.81 | USP30 (0.61) | USP30KEAP1NFE2L2STSACHE | |
| SCHEMBL24404862 | 0.81 | USP30 (0.61) | USP30KEAP1NFE2L2STSACHE | |
| SCHEMBL16633583 | 0.81 | USP30 (0.61) | USP30KEAP1NFE2L2STSACHE | |
| SCHEMBL2292403 | 0.78 | USP30 (0.53) | USP30KEAP1NFE2L2STSACHE | |
| SCHEMBL2292408 | 0.78 | USP30 (0.53) | USP30KEAP1NFE2L2STSACHE | |
| SCHEMBL517515 | 0.78 | USP30 (0.53) | USP30KEAP1NFE2L2STSACHE | |
| SCHEMBL2273817 | 0.78 | USP30 (0.53) | USP30KEAP1NFE2L2STSACHE | |
| SCHEMBL5768083 | 0.78 | USP30 (0.53) | USP30KEAP1NFE2L2STSACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260116888-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | NOVARTIS AG (CH) | 2026-04-30 | — | — | US | disclosed |
| US-20260001887-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. | 2026-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260116888-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | CDK4, CCNC, CDK6 | USP30 2710/4885KEAP1 905/4885NFE2L2 1364/4885 |
| US-20260001887-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | CDK4, CCNC, CDK2 | USP30 2589/4885KEAP1 1186/4885NFE2L2 2338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.