Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3371779 | 0.90 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL22539760 | 0.88 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2GAAPOLBKDM2B | |
| SCHEMBL16695584 | 0.88 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2GAAPOLBKDM2B | |
| SCHEMBL22539789 | 0.86 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2GAAPOLB | |
| SCHEMBL10859973 | 0.86 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL19617393 | 0.86 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2GAAPOLB | |
| SCHEMBL13291085 | 0.85 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2AL3MBTL3 | |
| SCHEMBL3273617 | 0.85 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2AL3MBTL3 | |
| SCHEMBL3273616 | 0.85 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2AL3MBTL3 | |
| SCHEMBL8297279 | 0.83 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MEN1KMT2AL3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817109-B1 | MIXED-MODAL ANION-EXCHANGE TYPE SEPARATION MATERIAL | MERCK PATENT GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |
| US-7648636-B2 | A chromatographic support including an immobilized ligand which combines an anion-exchange domain comprising an oligocyclic aza compound with endocyclic nitrogen and a non-ionic, second binding domain to allow adjustment of the overall hydrophobicity/hydrophilicity; separation; purification; peptides | MERCK PATENT GMBH (DE) | 2010-01-19 | — | — | US | disclosed |
| US-20080164211-A1 | Mixed-Modal Anion-Exchanged Type Separation Material | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
| EP-1817109-A1 | MIXED-MODAL ANION-EXCHANGE TYPE SEPARATION MATERIAL | Merck Patent GmbH (DE) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006058623-A1 | MIXED-MODAL ANION-EXCHANGE TYPE SEPARATION MATERIAL | MERCK PATENT GMBH (DE) | 2006-06-08 | — | — | WO | disclosed |
| US-4971958-A | CALCIUM METABOLISM | BOEHRINGER MANNHEIM GMBH (DE) | 1990-11-20 | — | — | US | disclosed |