SCHEMBL31757775

SCHEMBL31757775

COC(=O)[C@@H](O)CN(C)C(=O)OC(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA14 Q9ULX7 3/20 0.34
CA12 O43570 2/20 0.34
CTSK P43235 5/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
DGAT1 O75907 1/20 0.33
CYP2D6 P10635 1/20 0.33
CA7 P43166 1/20 0.33
PSEN1 P49768 2/20 0.33
PSEN2 P49810 2/20 0.33
APH1B Q8WW43 2/20 0.33
NCSTN Q92542 2/20 0.33
APH1A Q96BI3 2/20 0.33
PSENEN Q9NZ42 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
HDAC6 Q9UBN7 2/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
KLK5 Q9Y337 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3099876 1.00 CA14 (0.34) CA14CA12CTSKCA1CA2
SCHEMBL22711184 0.85 CA14 (0.36) CA14CA12CTSKCA1CA2
SCHEMBL22711187 0.85 CA14 (0.36) CA14CA12CTSKCA1CA2
SCHEMBL18673512 0.83 CA14 (0.35) CA14CA12CTSKCA1CA2
SCHEMBL16517603 0.83 CTSK (0.38) CA14CA12CTSKCA1CA2
SCHEMBL17898136 0.83 CA14 (0.37) CA14CA12CTSKCA1CA2
SCHEMBL14750621 0.82 MEN1 (0.34) CA14CA12CTSKCA1CA2
SCHEMBL31757748 0.81 CA14 (0.33) CA14CA12CTSKCA1CA2
SCHEMBL25706123 0.81 CA14 (0.33) CA14CA12CA1CA2DGAT1
SCHEMBL16532598 0.81 CA12 (0.34) CA14CA12CA1CA2DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP3, DPP7, DPP9 CA14 632/4885CA12 716/4885CTSK 82/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.