SCHEMBL31757886

SCHEMBL31757886

CC(C)(C)OC(=O)N[C@H](CC(=O)O)c1ccccc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CTSS P25774 4/20 0.44
▸ CTSK P43235 3/20 0.44
▸ ATM Q13315 1/20 0.44
▸ MEN1 O00255 2/20 0.43
▸ KMT2A Q03164 2/20 0.43
▸ NPSR1 Q6W5P4 2/20 0.43
▸ CTSL P07711 1/20 0.43
▸ CTSB P07858 1/20 0.43
▸ PPARA Q07869 2/20 0.42
▸ PPARG P37231 1/20 0.42
▸ ALDH1A1 P00352 2/20 0.42
▸ CTSA P10619 2/20 0.41
▸ ACE P12821 1/20 0.41
▸ LMNA P02545 1/20 0.41
▸ PKM P14618 1/20 0.41
▸ HPGD P15428 1/20 0.41
▸ ALOX15 P16050 1/20 0.41
▸ TSHR P16473 1/20 0.41
▸ XBP1 P17861 1/20 0.41
▸ HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31757758 0.86 CTSA (0.55) CTSA
SCHEMBL19744371 0.86 CTSA (0.55) CTSA
SCHEMBL19744367 0.86 CTSA (0.55) CTSA
SCHEMBL17841293 0.85 CTSA (0.50) CTSSCTSKCTSA
SCHEMBL27603568 0.85 CTSA (0.51) CTSA
SCHEMBL19744343 0.85 CYP26A1 (0.53) CTSSCTSKATMMEN1KMT2A
SCHEMBL1157183 0.85 CTSA (0.50) CTSSCTSKCTSA
SCHEMBL1147244 0.85 CTSA (0.56) CTSA
SCHEMBL19744342 0.85 CYP26A1 (0.53) CTSSCTSKATMMEN1KMT2A
SCHEMBL4883355 0.85 CTSA (0.51) CTSA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP3, DPP7, DPP9 CTSS 265/4885CTSK 82/4885ATM 4663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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