Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31757758 | 1.00 | CTSA (0.55) | CTSA | |
| SCHEMBL19744371 | 1.00 | CTSA (0.55) | CTSA | |
| SCHEMBL31757886 | 0.86 | CTSS (0.44) | CTSA | |
| SCHEMBL29748599 | 0.86 | JAK2 (0.43) | — | |
| SCHEMBL22457063 | 0.86 | JAK2 (0.43) | — | |
| SCHEMBL29747547 | 0.86 | JAK2 (0.43) | — | |
| SCHEMBL10270101 | 0.86 | JAK2 (0.43) | — | |
| SCHEMBL14879141 | 0.86 | CTSA (0.62) | CTSA | |
| SCHEMBL1157183 | 0.85 | CTSA (0.50) | CTSA | |
| SCHEMBL1147244 | 0.85 | CTSA (0.56) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017222083-A1 | NOVEL COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2017-12-28 | — | — | WO | disclosed |