SCHEMBL31758276

SCHEMBL31758276

CC(C)(C)OC(=O)[C@H](CCCCNC(=O)OCC1c2ccccc2-c2ccccc21)NC(=O)CCCCCC(=O)O

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 5/20 0.67
▸ TLR2 O60603 3/20 0.51
▸ TLR1 Q15399 1/20 0.51
▸ NPSR1 Q6W5P4 6/20 0.44
▸ MEN1 O00255 4/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ KLK7 P49862 1/20 0.43
▸ KLK5 Q9Y337 1/20 0.43
▸ MAPT P10636 3/20 0.43
▸ TDP1 Q9NUW8 2/20 0.43
▸ MDM2 Q00987 1/20 0.43
▸ PAX8 Q06710 1/20 0.43
▸ POLB P06746 2/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ ITGB3 P05106 1/20 0.42
▸ ITGA2B P08514 1/20 0.42
▸ FOLH1 Q04609 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20450603 0.92 KMT2A (0.57) KMT2ATLR2TLR1NPSR1MEN1
SCHEMBL20450605 0.92 KMT2A (0.57) KMT2ATLR2TLR1NPSR1MEN1
SCHEMBL20450575 0.92 KMT2A (0.57) KMT2ATLR2TLR1NPSR1MEN1
SCHEMBL20450573 0.92 KMT2A (0.57) KMT2ATLR2TLR1NPSR1MEN1
SCHEMBL31696731 0.92 KMT2A (0.60) KMT2ATLR2TLR1NPSR1MEN1
SCHEMBL24235695 0.90 KMT2A (0.57) KMT2ATLR2TLR1NPSR1MEN1
SCHEMBL20530075 0.90 KMT2A (0.54) KMT2ATLR2TLR1KLK7KLK5
SCHEMBL20530072 0.90 KMT2A (0.54) KMT2ATLR2TLR1KLK7KLK5
SCHEMBL17746997 0.89 KMT2A (0.58) KMT2ATLR2TLR1KLK7KLK5
SCHEMBL17746999 0.89 KMT2A (0.58) KMT2ATLR2TLR1KLK7KLK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS TRUSTEES OF TUFTS COLLEGE 2026-01-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS FIBP, FRS2, FGFR1 KMT2A 3715/4885TLR2 4438/4885TLR1 4520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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