SCHEMBL31696731

SCHEMBL31696731

CC(C)(C)OC(=O)[C@H](CCCCNC(=O)CCCCC(=O)O)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.63

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.60
▸ TLR2 O60603 4/20 0.48
▸ TLR1 Q15399 1/20 0.48
▸ MDM2 Q00987 2/20 0.47
▸ MDM4 O15151 1/20 0.44
▸ TP53 P04637 1/20 0.44
▸ MEN1 O00255 1/20 0.43
▸ ALDH1A1 P00352 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ SIRT2 Q8IXJ6 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31758276 0.92 KMT2A (0.67) KMT2ATLR2TLR1MDM2MEN1
SCHEMBL22367804 0.90 KMT2A (0.55) KMT2ATLR2MDM2MDM4TP53
SCHEMBL20450573 0.88 KMT2A (0.57) KMT2ATLR2TLR1MEN1ALDH1A1
SCHEMBL20450603 0.88 KMT2A (0.57) KMT2ATLR2TLR1MEN1ALDH1A1
SCHEMBL20450575 0.88 KMT2A (0.57) KMT2ATLR2TLR1MEN1ALDH1A1
SCHEMBL20450605 0.88 KMT2A (0.57) KMT2ATLR2TLR1MEN1ALDH1A1
SCHEMBL18571525 0.88 TLR2 (0.56) KMT2ATLR2TLR1MDM2MDM4
SCHEMBL18571434 0.88 TLR2 (0.56) KMT2ATLR2TLR1MDM2MDM4
SCHEMBL15387319 0.88 TLR2 (0.60) KMT2ATLR2TLR1MDM2SIRT2
SCHEMBL15387434 0.88 TLR2 (0.60) KMT2ATLR2TLR1MDM2SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12521455-B2 Kisspeptin receptor (KISS1R) targeted therapeutics and uses thereof RADIONETICS ONCOLOGY, INC. (US) 2026-01-13 — — US disclosed
WO-2025217074-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2025-10-16 — — WO disclosed
US-20250312499-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. 2025-10-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250312499-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF KISS1R, GNRHR, PROKR1 KMT2A 868/4885TLR2 2343/4885TLR1 1471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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