SCHEMBL31758278

SCHEMBL31758278

O=C(CCCc1ccc(I)cc1)NCCCC[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ALB P02768 11/20 0.62
▸ MDM2 Q00987 3/20 0.55
▸ TLR2 O60603 2/20 0.50
▸ CA9 Q16790 1/20 0.50
▸ KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25728007 0.91 MDM2 (0.55) ALBMDM2TLR2KMT2A
SCHEMBL30905431 0.90 ALB (0.53) ALBMDM2TLR2CA9KMT2A
SCHEMBL22021737 0.90 MDM2 (0.57) ALBMDM2TLR2KMT2A
SCHEMBL20530026 0.89 ALB (0.53) ALBMDM2TLR2CA9KMT2A
SCHEMBL24193189 0.89 MDM2 (0.55) ALBMDM2TLR2KMT2A
SCHEMBL21963412 0.89 MDM2 (0.55) ALBMDM2TLR2KMT2A
SCHEMBL22021738 0.87 MDM2 (0.56) ALBMDM2TLR2KMT2A
SCHEMBL24193273 0.86 MDM2 (0.55) ALBMDM2TLR2KMT2A
SCHEMBL15964082 0.86 TLR2 (0.49) ALBMDM2TLR2CA9KMT2A
SCHEMBL14708957 0.86 ALB (0.47) ALBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS TRUSTEES OF TUFTS COLLEGE 2026-01-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007787-A1 RADIOPHARMACEUTICAL SMALL MOLECULE INHIBITORS OF FIBROBLAST ACTIVATION PROTEIN FOR TARGETED THERAPY AND DIAGNOSTIC IMAGING OF DESMOPLASTIC TUMORS FIBP, FRS2, FGFR1 ALB 3527/4885MDM2 1169/4885TLR2 4438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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