Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 5/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | MDM4 | O15151 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 2/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21963412 | 0.93 | MDM2 (0.55) | MDM2SIRT2SIRT1KMT2ATLR2 | |
| SCHEMBL24193189 | 0.93 | MDM2 (0.55) | MDM2SIRT2SIRT1KMT2ATLR2 | |
| SCHEMBL22021739 | 0.91 | MDM2 (0.56) | MDM2SIRT2SIRT1KMT2ATLR2 | |
| SCHEMBL22021737 | 0.91 | MDM2 (0.57) | MDM2KMT2ATLR2MDM4TP53 | |
| SCHEMBL24193273 | 0.90 | MDM2 (0.55) | MDM2SIRT2SIRT1KMT2ATLR2 | |
| SCHEMBL31758278 | 0.87 | ALB (0.62) | MDM2KMT2ATLR2ALB | |
| SCHEMBL260631 | 0.84 | KMT2A (0.66) | MDM2KMT2ATLR2MDM4TP53 | |
| SCHEMBL178698 | 0.84 | KMT2A (0.66) | MDM2KMT2ATLR2MDM4TP53 | |
| SCHEMBL178733 | 0.84 | KMT2A (0.66) | MDM2KMT2ATLR2MDM4TP53 | |
| SCHEMBL29528567 | 0.84 | KMT2A (0.66) | MDM2KMT2ATLR2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102348-A1 | THIOAMIDE-CONTAINING COMPOSITIONS AND METHODS OF USE THEREOF | DIMAGNO STEPHEN (US) | 2020-05-22 | — | — | WO | disclosed |