Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17586454 | 1.00 | IP6K1 (0.47) | IP6K1BACE1LMNAMAPTGPR119 | |
| SCHEMBL22479327 | 0.91 | BACE1 (0.41) | IP6K1BACE1GPR119OPRM1OPRL1 | |
| SCHEMBL20955524 | 0.88 | IP6K1 (0.48) | IP6K1MAPTHRH3OPRM1OPRL1 | |
| SCHEMBL13480003 | 0.88 | OPRM1 (0.52) | IP6K1LMNAGPR119ALDH1A1HRH3 | |
| SCHEMBL17586461 | 0.87 | USP30 (0.43) | IP6K1BACE1LMNAMAPTALDH1A1 | |
| SCHEMBL31758493 | 0.87 | USP30 (0.43) | IP6K1BACE1LMNAMAPTALDH1A1 | |
| SCHEMBL25354443 | 0.87 | IP6K1 (0.58) | IP6K1HRH3OPRM1OPRL1OPRD1 | |
| SCHEMBL4976498 | 0.87 | OPRM1 (0.53) | IP6K1GPR119HRH3OPRM1OPRL1 | |
| SCHEMBL4976495 | 0.87 | OPRM1 (0.53) | IP6K1GPR119HRH3OPRM1OPRL1 | |
| SCHEMBL30623394 | 0.87 | IP6K1 (0.58) | IP6K1HRH3OPRM1OPRL1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260008760-A1 | DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF | INSMED INCORPORATED | 2026-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260008760-A1 | DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF | DPP9, DPP7, DPP4 | IP6K1 1623/4885BACE1 268/4885LMNA 3945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.