Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30206032 | 1.00 | ATM (0.65) | ATMTSHRALDH1A1APOBEC3AAPOBEC3G | |
| SCHEMBL12368660 | 1.00 | ATM (0.65) | ATMTSHRALDH1A1APOBEC3AAPOBEC3G | |
| SCHEMBL3272065 | 1.00 | ATM (0.65) | ATMTSHRALDH1A1APOBEC3AAPOBEC3G | |
| SCHEMBL15138186 | 1.00 | ATM (0.65) | ATMTSHRALDH1A1APOBEC3AAPOBEC3G | |
| SCHEMBL31707416 | 1.00 | ATM (0.65) | ATMTSHRALDH1A1APOBEC3AAPOBEC3G | |
| SCHEMBL8401652 | 0.85 | ALDH1A1 (0.59) | ATMTSHRALDH1A1APOBEC3AAPOBEC3G | |
| SCHEMBL8401942 | 0.85 | ALDH1A1 (0.59) | ATMTSHRALDH1A1APOBEC3AAPOBEC3G | |
| SCHEMBL3272061 | 0.85 | ALDH1A1 (0.59) | ATMTSHRALDH1A1APOBEC3AAPOBEC3G | |
| SCHEMBL8401692 | 0.85 | ALDH1A1 (0.59) | ATMTSHRALDH1A1APOBEC3AAPOBEC3G | |
| SCHEMBL8401694 | 0.85 | ALDH1A1 (0.59) | ATMTSHRALDH1A1APOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260008787-A1 | FUSED RING KRAS INHIBITORS FOR TREATING DISEASE | BLOSSOMHILL THERAPEUTICS INC (US) | 2026-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260008787-A1 | FUSED RING KRAS INHIBITORS FOR TREATING DISEASE | KRAS, NRAS, HRAS | ATM 1382/4885TSHR 197/4885ALDH1A1 2043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.