Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11515753 | 0.80 | CA12 (0.50) | TSHRTRPA1TAAR1SLC6A2SIGMAR1 | |
| SCHEMBL27464190 | 0.79 | ATM (0.43) | TSHRTRPA1TAAR1SLC6A2SIGMAR1 | |
| SCHEMBL6388904 | 0.78 | TAAR1 (0.52) | TSHRTRPA1TAAR1SLC6A2SIGMAR1 | |
| SCHEMBL7637871 | 0.75 | TSHR (0.54) | TSHRTRPA1HPGDCYP3A4MAPK1 | |
| SCHEMBL23253273 | 0.75 | TRPA1 (0.48) | TSHRTRPA1TAAR1SLC6A2SIGMAR1 | |
| SCHEMBL14962697 | 0.75 | TAAR1 (0.54) | TSHRTRPA1TAAR1SLC6A2SIGMAR1 | |
| SCHEMBL11514993 | 0.75 | TAAR1 (0.54) | TSHRTRPA1TAAR1SLC6A2SIGMAR1 | |
| SCHEMBL10793304 | 0.73 | TAAR1 (0.56) | TSHRTRPA1TAAR1SLC6A2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL8805226 | 0.73 | TAAR1 (0.52) | TSHRTRPA1TAAR1SLC6A2SIGMAR1 | |
| SCHEMBL27791495 | 0.73 | TSHR (0.61) | TSHRTRPA1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100018920-A1 | REACTION AND SEPARATION METHODS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-01-28 | — | — | US | disclosed |
| EP-1269170-A4 | REACTION AND SEPARATION METHODS | UNIV PITTSBURGH (US) | 2007-10-31 | — | — | EP | disclosed |
| US-20040197829-A1 | Reaction and separation methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-10-07 | — | — | US | disclosed |
| US-6749756-B1 | Reaction and separation methods | UNIVERSITY OF PITTSBURGH | 2004-06-15 | — | — | US | disclosed |
| EP-1269170-A1 | REACTION AND SEPARATION METHODS | UNIVERSITY OF PITTSBURGH (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001061332-A1 | REACTION AND SEPARATION METHODS | UNIVERSITY OF PITTSBURGH (US) | 2001-08-23 | — | — | WO | disclosed |