SCHEMBL317617

SCHEMBL317617

CNc1cccnc1N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30844245 1.00
Hydrochloric Acid SCHEMBL29435773 0.98 BACE1 (0.50)
SCHEMBL19274918 0.79
SCHEMBL3060454 0.77 BACE1 (0.61)
SCHEMBL1496449 0.77 IDO1 (0.47)
SCHEMBL13818425 0.75 POLB (0.62)
SCHEMBL40201 0.74 RRM2 (0.40)
SCHEMBL883520 0.74
SCHEMBL29828009 0.74 RRM2 (0.40)
SCHEMBL6449076 0.74 RRM2 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4745134-A1 PROTEIN ARGINASE METHYLTRANSFERASE-5 INHIBITOR AND MEDICAL USE THEREOF Jiangsu Yahong Meditech Co., Ltd. (CN) 2026-05-20 EP disclosed
WO-2025016323-A1 PROTEIN ARGINASE METHYLTRANSFERASE-5 INHIBITOR AND MEDICAL USE THEREOF 江苏亚虹医药科技股份有限公司 2025-01-23 WO disclosed
CN-117603134-A Nitration process for pyridine derivatives, process for preparing 2-nitro-3-aminopyridine and intermediates 上海凌凯医药科技有限公司 2024-02-27 CN disclosed
CN-113307765-A Pyridine methylamine compound and preparation method thereof 上海泰坦科技股份有限公司 2021-08-27 CN disclosed
US-11081651-B2 Organic semiconductor element, organic semiconductor composition, method of manufacturing organic semiconductor film, organic semiconductor film, and compound and polymer using the same FUJIFILM CORPORATION (JP) 2021-08-03 US disclosed
EP-2585462-B1 FUSED HETEROCYCLIC COMPOUNDS AS PHOSPHODIESTERASES (PDES) INHIBITORS TAKEDA PHARMACEUTICALS CO (JP) 2020-02-26 EP disclosed
EP-3091012-B1 CCR2 RECEPTOR ANTAGONISTS AND USES THEREOF CENTREXION THERAPEUTICS CORP (US) 2018-04-11 EP disclosed
WO-2017009208-A1 USE OF CORROSION INHIBITORS FOR FUELS AND LUBRICANTS BASF SE (DE) 2017-01-19 WO disclosed
US-9226921-B2 Fused heterocyclic compounds as phosphodiesterases (PDES) inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-01-05 US disclosed
US-9226921-B2 Fused heterocyclic compounds as phosphodiesterases (PDES) inhibitors TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2016-01-05 US disclosed
EP-0729948-A1 The production of 3-alkylamino-2-piperazinylpyridines THE UPJOHN COMPANY (US) 1996-09-04 EP disclosed
EP-0690848-A1 PIPERAZINYLPYRIDINYL WATER CLATHRATES PHARMACIA &amp; UPJOHN COMPANY (US) 1996-01-10 EP disclosed
WO-1994022836-A2 PIPERAZINYLPYRIDINYL WATER CLATHRATES THE UPJOHN COMPANY (US) 1994-10-13 WO disclosed
EP-0174272-B1 PROCESS FOR THE PREPARATION OF DIMETHYLMALEIC ANHYDRIDE CIBA-GEIGY AG (CH) 1988-08-31 EP disclosed
EP-0175641-B1 PROCESS FOR THE PREPARATION OF DIMETHYLMALEIC ANHYDRIDE CIBA-GEIGY AG (CH) 1988-02-24 EP disclosed
US-4644069-A HEATING MALEIC ACID OR ANHYDRIDE WITH AN AMIDINE OR ITS SALT CIBA-GEIGY CORPORATION (US) 1987-02-17 US disclosed
US-4639531-A HETEROCYCLIC AMIDINE CATALYST CIBA-GEIGY CORPORATION (US) 1987-01-27 US disclosed
EP-0175641-A1 Process for the preparation of dimethylmaleic anhydride CIBA-GEIGY AG (CH) 1986-03-26 EP disclosed
EP-0174272-A1 Process for the preparation of dimethylmaleic anhydride CIBA-GEIGY AG (CH) 1986-03-12 EP disclosed
EP-0039920-A2 Triazaloquinoxalin-1,4-diones USV PHARMACEUTICAL CORPORATION (US) 1981-11-18 EP disclosed