Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RRM2 | P31350 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29828009 | 1.00 | RRM2 (0.40) | RRM2NCOA1NCOA3KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL29508626 | 0.98 | RRM2 (0.39) | RRM2NCOA1NCOA3KDM4ENPC1 | |
| SCHEMBL24029047 | 0.81 | GRM5 (0.56) | KDM4ENPC1RAB9APOLBL3MBTL1 | |
| SCHEMBL1746368 | 0.81 | GRM5 (0.49) | RRM2NCOA1NCOA3KDM4ENPC1 | |
| SCHEMBL12172562 | 0.80 | DHODH (0.49) | KDM4ENPC1RAB9AMAPTTDP1 | |
| SCHEMBL22000709 | 0.80 | RRM2 (0.38) | RRM2NCOA1NCOA3KDM4ENPC1 | |
| SCHEMBL22300096 | 0.80 | TSHR (0.36) | RRM2NCOA1NCOA3KDM4ENPC1 | |
| SCHEMBL22600380 | 0.80 | GRM5 (0.41) | RRM2NCOA1NCOA3KDM4ENPC1 | |
| SCHEMBL12172496 | 0.80 | DHODH (0.53) | NPC1RAB9AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL23747187 | 0.80 | GRM5 (0.38) | RRM2NCOA1NCOA3KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 320 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8211859-B2 | α-galactoceramide analogs, their methods of manufacture, intermediate compounds useful in these methods, and pharmaceutical compositions containing them | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-07-03 | — | — | US | claimed |
| US-20110028411-A1 | ALPHA-GALACTOCERAMIDE ANALOGS, THEIR METHODS OF MANUFACTURE, INTERMEDIATE COMPOUNDS USEFUL IN THESE METHODS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFQUE (FR) | 2011-02-03 | — | — | US | claimed |
| WO-2008047249-A9 | ALPHA-GALACTOCERAMIDE ANALOGS, THEIR METHODS OF MANUFACTURE, INTERMEDIATE COMPOUNDS USEFUL IN THESE METHODS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2009-12-23 | — | — | WO | claimed |
| EP-2099813-A2 | ALPHA-GALACTOCERAMIDE ANALOGS, THEIR METHODS OF MANUFACTURE, INTERMEDIATE COMPOUNDS USEFUL IN THESE METHODS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Centre National de la Recherche Scientifique (FR) | 2009-09-16 | — | — | EP | claimed |
| US-7511135-B2 | Method for manufacture of ceftiofur | LUPIN LIMITED (IN) | 2009-03-31 | — | — | US | claimed |
| WO-2008047249-A2 | ALPHA-GALACTOCERAMIDE ANALOGS, THEIR METHODS OF MANUFACTURE, INTERMEDIATE COMPOUNDS USEFUL IN THESE METHODS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2008-04-24 | — | — | WO | claimed |
| EP-1556388-B1 | A METHOD FOR MANUFACTURE OF CEFTIOFUR | LUPIN LTD (IN) | 2007-09-19 | — | — | EP | claimed |
| US-20060149054-A1 | Method for manufacture of ceftiofur | LUPIN LIMITED (IN) | 2006-07-06 | — | — | US | claimed |
| EP-1556388-A2 | A METHOD FOR MANUFACTURE OF CEFTIOFUR | Lupin Limited (IN) | 2005-07-27 | — | — | EP | claimed |
| WO-2004039811-A2 | A METHOD FOR MANUFACTURE OF CEFTIOFUR | LUPIN LIMITED (IN) | 2004-05-13 | — | — | WO | claimed |
| EP-0068804-B1 | PROCESS FOR PRODUCING SUBSTANTIALLY LINEAR CARBONATE POLYMER | PPG INDUSTRIES, INC. (US) | 1986-04-30 | — | — | EP | claimed |
| EP-0068804-A1 | Process for producing substantially linear carbonate polymer | PPG INDUSTRIES, INC. (US) | 1983-01-05 | — | — | EP | claimed |
| US-4365055-A | Process for producing substantially linear carbonate polymer | PPG INDUSTRIES, INC. (US) | 1982-12-21 | — | — | US | claimed |
| EP-3383386-B1 | MODULATORS OF CHEMOKINE RECEPTORS | CHEMOCENTRYX INC (US) | 2024-02-14 | — | — | EP | disclosed |
| US-11820759-B2 | Modulators of chemokine receptors | CHEMOCENTRYX, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| WO-2023116877-A1 | HETEROCYCLIC COMPOUND AS TEAD INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-06-29 | — | — | WO | disclosed |
| US-4489189-A | FROM TETRABROMOBISPHENOL A AND ETHYLENE GLYCOL | PPG INDUSTRIES, INC. (US) | 1984-12-18 | — | — | US | disclosed |
| US-4414396-A | FIREPROOFING | PPG INDUSTRIES, INC. (US) | 1983-11-08 | — | — | US | disclosed |
| EP-0068804-A1 | Process for producing substantially linear carbonate polymer | PPG INDUSTRIES, INC. (US) | 1983-01-05 | — | — | EP | disclosed |
| US-4365055-A | Process for producing substantially linear carbonate polymer | PPG INDUSTRIES, INC. (US) | 1982-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060149054-A1 | Method for manufacture of ceftiofur | APEH, COASY, PCMT1 | RRM2 4109/4885NCOA1 4775/4885NCOA3 4794/4885 |
| US-11820759-B2 | Modulators of chemokine receptors | CCR5, CXCR3, CCR2 | RRM2 1788/4885NCOA1 504/4885NCOA3 432/4885 |
| US-20110028411-A1 | ALPHA-GALACTOCERAMIDE ANALOGS, THEIR METHODS OF MANUFACTURE, INTERMEDIATE COMPOUNDS USEFUL IN THESE METHODS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GALE, GALNT14, GALC | RRM2 1664/4885NCOA1 4705/4885NCOA3 4464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.