SCHEMBL3176733

SCHEMBL3176733

CCc1ccc2c(c1)C(C)(C)CCC2(C)C

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RXRA P19793 8/20 0.54
RXRB P28702 5/20 0.54
RXRG P48443 5/20 0.54
CYP26B1 Q9NR63 8/20 0.51
CYP26A1 O43174 7/20 0.51
RARA P10276 2/20 0.46
RARB P10826 2/20 0.46
RARG P13631 2/20 0.46
PPARG P37231 2/20 0.43
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2897524 0.84 CYP26B1 (0.53) RXRARXRBRXRGCYP26B1CYP26A1
SCHEMBL3546404 0.82 RXRA (0.53) RXRARXRBRXRGCYP26B1CYP26A1
SCHEMBL1616186 0.82 RXRA (0.53) RXRARXRBRXRGCYP26B1CYP26A1
SCHEMBL2312146 0.82 RXRA (0.53) RXRARXRBRXRGCYP26B1CYP26A1
SCHEMBL2095481 0.82 RXRA (0.57) RXRARXRBRXRGCYP26B1CYP26A1
SCHEMBL14286073 0.82 RXRA (0.53) RXRARXRBRXRGCYP26B1CYP26A1
SCHEMBL694638 0.82 RXRA (0.53) RXRARXRBRXRGCYP26B1CYP26A1
SCHEMBL12743622 0.82 RXRA (0.53) RXRARXRBRXRGCYP26B1CYP26A1
SCHEMBL6909472 0.81 CYP26B1 (0.50) RXRARXRBRXRGCYP26B1CYP26A1
SCHEMBL9770732 0.80 ESR2 (0.38) RXRARXRBRXRGCYP26B1CYP26A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11637257-B2 Electroluminescent material ink and electroluminescent device thereof GUANGDONG JUHUA PRINTED DISPLAY TECHNOLOGY CO. LTD (CN) 2023-04-25 US claimed
CN-109929328-B Composite ink and preparation method and device thereof TCL科技集团股份有限公司 2021-10-22 CN claimed
US-20200373508-A1 ELECTROLUMINESCENT MATERIAL INK AND ELECTROLUMINESCENT DEVICE THEREOF GUANGDONG JUHUA PRINTED DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-11-26 US claimed
CN-108948865-B Electroluminescent material ink and electroluminescent device thereof 广东聚华印刷显示技术有限公司 2020-07-10 CN claimed
CN-109929328-A A kind of compound ink and preparation method thereof, device TCL集团股份有限公司 2019-06-25 CN claimed
US-11637257-B2 Electroluminescent material ink and electroluminescent device thereof GUANGDONG JUHUA PRINTED DISPLAY TECHNOLOGY CO. LTD (CN) 2023-04-25 US disclosed
US-11180489-B2 Sphingosine kinase inhibitor amidoxime prodrugs U niversity of Virginia Patent Foundation (US) 2021-11-23 US disclosed
CN-109929328-B Composite ink and preparation method and device thereof TCL科技集团股份有限公司 2021-10-22 CN disclosed
US-20200373508-A1 ELECTROLUMINESCENT MATERIAL INK AND ELECTROLUMINESCENT DEVICE THEREOF GUANGDONG JUHUA PRINTED DISPLAY TECHNOLOGY CO., LTD. (CN) 2020-11-26 US disclosed
US-20200308159-A1 SPHINGOSINE KINASE INHIBITOR AMIDOXIME PRODRUGS SPHYNKX THERAPEUTICS, LLC 2020-10-01 US disclosed
CN-108948865-B Electroluminescent material ink and electroluminescent device thereof 广东聚华印刷显示技术有限公司 2020-07-10 CN disclosed
CN-109929328-A A kind of compound ink and preparation method thereof, device TCL集团股份有限公司 2019-06-25 CN disclosed
US-5149705-A Treatment of psoriasis ALLERGAN, INC. (US) 1992-09-22 US disclosed
EP-0294746-A1 Bicyclic nitro compounds L. GIVAUDAN & CIE Société Anonyme (CH) 1988-12-14 EP disclosed
EP-0284261-A1 Acetylenes disubstituted with a heteroaromatic group and a tetralin group having retinoid like activity ALLERGAN, INC (US) 1988-09-28 EP disclosed
CN-88101234-A Acetylenes disubstituted with heteroaryl and tetralinyl having retinoid-like activity 1988-09-28 CN disclosed
EP-0040338-A2 Process for the preparation of acylated indanes and tetrahydronaphthalenes INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-11-25 EP disclosed
US-4178311-A Process for the production of compounds useful in perfumery INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-12-11 US disclosed
EP-0004914-A1 Process for the production of compounds useful in perfumery INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-10-31 EP disclosed
US-4162256-A Process for the production of compounds useful in perfumery INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200308159-A1 SPHINGOSINE KINASE INHIBITOR AMIDOXIME PRODRUGS SPHK1, SPHK2, S1PR2 RXRA 4349/4885RXRB 4100/4885RXRG 4421/4885
US-11180489-B2 Sphingosine kinase inhibitor amidoxime prodrugs SPHK1, SPHK2, S1PR2 RXRA 4349/4885RXRB 4100/4885RXRG 4421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.