Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 3/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.31 |
| ▸ | ODC1 | P11926 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28216351 | 1.00 | GRB2 (0.36) | GRB2ALOX15BLMPMP22KMT2A | |
| Trifluoroacetic Acid SCHEMBL3176290 | 0.87 | GRB2 (0.36) | GRB2ALOX15BLMPMP22KMT2A | |
| Trifluoroacetic Acid SCHEMBL29981273 | 0.87 | GRB2 (0.36) | GRB2ALOX15BLMPMP22KMT2A | |
| Asparagine SCHEMBL30183111 | 0.87 | ALOX15 (0.45) | GRB2ALOX15BLMPMP22KMT2A | |
| Asparagine SCHEMBL29663907 | 0.87 | ALOX15 (0.45) | GRB2ALOX15BLMPMP22KMT2A | |
| SCHEMBL1263698 | 0.83 | — | — | |
| SCHEMBL195837 | 0.83 | — | — | |
| SCHEMBL195836 | 0.83 | — | — | |
| Trifluoroacetic Acid SCHEMBL20164118 | 0.82 | ALOX15 (0.38) | GRB2ALOX15BLMPMP22KMT2A | |
| Ammonia Solution, Strong SCHEMBL25331273 | 0.81 | ALOX15 (0.39) | ALOX15BLMPMP22KMT2ADPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645792-B2 | Prodrugs of propofol, compositions and uses thereof | XENOPORT, INC. (US) | 2010-01-12 | — | — | US | disclosed |
| US-20090005352-A1 | Prodrugs of Propofol, Compositions and Uses Thereof | XENOPORT, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| US-7241807-B2 | Prodrugs of propofol, compositions and uses thereof | XENOPORT, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| US-20060041011-A1 | Prodrugs of propofol, compositions and uses thereof | XENOPORT, INC. | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060041011-A1 | Prodrugs of propofol, compositions and uses thereof | CYP2C19, CYP3A5, CYP3A4 | GRB2 4848/4885ALOX15 638/4885BLM 3716/4885 |
| US-20090005352-A1 | Prodrugs of Propofol, Compositions and Uses Thereof | CYP2C19, CYP3A5, CYP3A4 | GRB2 4848/4885ALOX15 638/4885BLM 3716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.