Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3184793 | 0.90 | AR (0.56) | ARPGR | |
| SCHEMBL3173754 | 0.82 | AR (0.63) | ARPGR | |
| SCHEMBL3177707 | 0.81 | PGR (0.66) | ARPGR | |
| SCHEMBL3181351 | 0.81 | AR (0.64) | ARPGR | |
| SCHEMBL3175690 | 0.80 | PGR (0.51) | ARPGR | |
| SCHEMBL3181424 | 0.79 | PGR (0.51) | ARPGR | |
| SCHEMBL3167416 | 0.74 | PGR (0.64) | ARPGR | |
| SCHEMBL4611838 | 0.73 | PGR (1.00) | ARPGR | |
| SCHEMBL4598329 | 0.70 | PGR (0.66) | ARPGR | |
| SCHEMBL79633 | 0.70 | AR (0.57) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7652062-B2 | Cyanopyrrole-phenyl amide progesterone receptor modulators and uses thereof | WYETH LLC (US) | 2010-01-26 | — | — | US | claimed |
| EP-1909785-A2 | USE OF PROGESTERONE RECEPTOR MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2008-04-16 | — | — | EP | claimed |
| EP-1910284-A1 | CYANOPYRROLE-PHENYL AMIDE PROGESTERONE RECEPTOR MODULATORS AND USES THEREOF | Wyeth (US) | 2008-04-16 | — | — | EP | claimed |
| US-20080064673-A1 | Cyanopyrrole-phenyl amide progesterone receptor modulators and uses thereof | WYETH (US) | 2008-03-13 | — | — | US | claimed |
| US-7297713-B2 | Cyanopyrrole-phenyl amide progesterone receptor modulators and uses thereof | WYETH (US) | 2007-11-20 | — | — | US | claimed |
| WO-2007016211-A1 | CYANOPYRROLE-PHENYL AMIDE PROGESTERONE RECEPTOR MODULATORS AND USES THEREOF | WYETH (US) | 2007-02-08 | — | — | WO | claimed |
| WO-2007016385-A2 | USE OF SUBSTITUTED 5-AMINO-1H-PYRROLE-2-CARBONITRILE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2007-02-08 | — | — | WO | claimed |
| US-20070027201-A1 | Use of progesterone receptor modulators | WYETH (US) | 2007-02-01 | — | — | US | claimed |
| US-20070027125-A1 | Cyanopyrrole-phenyl progesterone receptor modulators and uses thereof | WYETH (US) | 2007-02-01 | — | — | US | claimed |
| US-7652062-B2 | Cyanopyrrole-phenyl amide progesterone receptor modulators and uses thereof | WYETH LLC (US) | 2010-01-26 | — | — | US | disclosed |
| EP-1909785-A2 | USE OF PROGESTERONE RECEPTOR MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2008-04-16 | — | — | EP | disclosed |
| EP-1910284-A1 | CYANOPYRROLE-PHENYL AMIDE PROGESTERONE RECEPTOR MODULATORS AND USES THEREOF | Wyeth (US) | 2008-04-16 | — | — | EP | disclosed |
| US-20080064673-A1 | Cyanopyrrole-phenyl amide progesterone receptor modulators and uses thereof | WYETH (US) | 2008-03-13 | — | — | US | disclosed |
| US-7297713-B2 | Cyanopyrrole-phenyl amide progesterone receptor modulators and uses thereof | WYETH (US) | 2007-11-20 | — | — | US | disclosed |
| WO-2007016211-A1 | CYANOPYRROLE-PHENYL AMIDE PROGESTERONE RECEPTOR MODULATORS AND USES THEREOF | WYETH (US) | 2007-02-08 | — | — | WO | disclosed |
| WO-2007016385-A2 | USE OF SUBSTITUTED 5-AMINO-1H-PYRROLE-2-CARBONITRILE DERIVATIVES AS PROGESTERONE RECEPTOR MODULATORS | WYETH (US) | 2007-02-08 | — | — | WO | disclosed |
| US-20070027201-A1 | Use of progesterone receptor modulators | WYETH (US) | 2007-02-01 | — | — | US | disclosed |
| US-20070027125-A1 | Cyanopyrrole-phenyl progesterone receptor modulators and uses thereof | WYETH (US) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064673-A1 | Cyanopyrrole-phenyl amide progesterone receptor modulators and uses thereof | PGR, GNRHR, PGRMC1 | AR 127/4885PGR 1/4885 |
| US-20070027125-A1 | Cyanopyrrole-phenyl progesterone receptor modulators and uses thereof | PGR, PGRMC1, PGRMC2 | AR 145/4885PGR 1/4885 |
| US-20070027201-A1 | Use of progesterone receptor modulators | GNRHR, PGR, FSHR | AR 28/4885PGR 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.