⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| T-Butylacetic Acid SCHEMBL27918136 | 0.92 | KDM4E (0.50) | — | |
| SCHEMBL30854909 | 0.84 | KDM4E (0.65) | — | |
| SCHEMBL48109 | 0.84 | KDM4E (0.65) | — | |
| Hydrochloric Acid SCHEMBL5406891 | 0.81 | KDM4E (0.70) | — | |
| SCHEMBL10887236 | 0.81 | KDM4E (0.62) | — | |
| SCHEMBL10887191 | 0.81 | KDM4E (0.62) | — | |
| SCHEMBL8581488 | 0.81 | KDM4E (0.62) | — | |
| SCHEMBL11439787 | 0.81 | KDM4E (0.62) | — | |
| SCHEMBL6733907 | 0.81 | KDM4E (0.62) | — | |
| SCHEMBL9819340 | 0.81 | KDM4E (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260083866-A1 | COMPOSITIONS TARGETING ENDOTHELIAL CELLS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2026-03-26 | — | — | US | claimed |
| WO-2024243545-A1 | COMPOSITIONS TARGETING ENDOTHELIAL CELLS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-11-28 | — | — | WO | claimed |
| US-8273787-B2 | Activated cytotoxic compounds for attachment to targeting molecules for the treatment of mammalian disease conditions | ONCONOVA THERAPEUTICS, INC (US) | 2012-09-25 | — | — | US | claimed |
| US-20100022615-A1 | ACTIVATED CYTOTOXIC COMPOUNDS FOR ATTACHMENT TO TARGETING MOLECULES FOR THE TREATMENT OF MAMMALIAN DISEASE CONDITIONS | ONCONOVA THERAPEUTICS, INC (US) | 2010-01-28 | — | — | US | claimed |
| WO-2008033475-A2 | ACTIVATED CYTOTOXIC COMPOUNDS FOR ATTACHMENT TO TARGETING MOLECULES FOR THE TREATMENT OF MAMMALIAN DISEASE CONDITIONS | ONCONOVA THERAPEUTICS, INC. (US) | 2008-03-20 | — | — | WO | claimed |
| EP-1317497-A4 | POLYESTER RESINS WITH IMPROVED PROPERTIES | POLYMERS AUSTRALIA PTY LTD (AU) | 2005-03-02 | — | — | EP | claimed |
| US-20040116619-A1 | Polyester resins with improved properties | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2004-06-17 | — | — | US | claimed |
| CN-1474842-A | Polyester resins with improved properties | �Ĵ����Ǿۺ���ع�����˾ | 2004-02-11 | — | — | CN | claimed |
| EP-1317497-A1 | POLYESTER RESINS WITH IMPROVED PROPERTIES | Polymers Australia PTY Limited (AU) | 2003-06-11 | — | — | EP | claimed |
| WO-2002022705-A1 | POLYESTER RESINS WITH IMPROVED PROPERTIES | POLYMERS AUSTRALIA PTY LTD (AU) | 2002-03-21 | — | — | WO | claimed |
| CN-122055373-A | Bridged tricyclic carbamoyl pyridone compounds and uses thereof | 吉利德科学公司 | 2026-05-15 | — | — | CN | disclosed |
| US-20260083866-A1 | COMPOSITIONS TARGETING ENDOTHELIAL CELLS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2026-03-26 | — | — | US | disclosed |
| WO-2024243545-A1 | COMPOSITIONS TARGETING ENDOTHELIAL CELLS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-11-28 | — | — | WO | disclosed |
| CN-116283647-A | Prodrug modulators that integrate stress pathways | 卡里科生命科学有限责任公司 | 2023-06-23 | — | — | CN | disclosed |
| WO-2020165600-A1 | BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF | BICYCLETX LIMITED (GB) | 2020-08-20 | — | — | WO | disclosed |
| WO-2002022705-A1 | POLYESTER RESINS WITH IMPROVED PROPERTIES | POLYMERS AUSTRALIA PTY LTD (AU) | 2002-03-21 | — | — | WO | disclosed |
| EP-1176953-A2 | TREATMENT OF A VARIETY OF PATHOLOGICAL CONDITIONS, INCLUDING SPASTICITY AND CONVULSIONS, BY EFFECTING MODULATION OF CNS ACTIVITY WITH ISOVALERAMIDE, ISOVALERIC ACID, OR A RELATED COMPOUND | NPS PHARMACEUTICALS, INC. (US) | 2002-02-06 | — | — | EP | disclosed |
| EP-1059930-A1 | COMPOSITIONS COMPRISING VALERIAN EXTRACTS, ISOVALERIC ACID OR DERIVATIVES THEREOF WITH A NSAID | NPS PHARMACEUTICALS, INC. (US) | 2000-12-20 | — | — | EP | disclosed |
| WO-2000051586-A2 | TREATING A VARIETY OF PATHOLOGICAL CONDITIONS, INCLUDING SPASTICITY AND CONVULSIONS, BY EFFECTING MODULATION OF CNS ACTIVITY WITH ISOVALERAMIDE, ISOVALERIC ACID, OR A RELATED COMPOUND | NPS PHARMACEUTICALS, INC. (US) | 2000-09-08 | — | — | WO | disclosed |
| WO-1999044623-A1 | COMPOSITIONS COMPRISING VALERIAN EXTRACTS, ISOVALERIC ACID OR DERIVATIVES THEREOF WITH A NSAID | NPS PHARMACEUTICALS, INC. (US) | 1999-09-10 | — | — | WO | disclosed |