Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633230 | 0.85 | MGAM (0.37) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL3178805 | 0.81 | CA12 (0.41) | MGAMGAASIMGAM2HSD17B10 | |
| SCHEMBL8139158 | 0.81 | MGAM (0.55) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL3167085 | 0.80 | TSHR (0.34) | TSHR | |
| SCHEMBL3161150 | 0.80 | KCNQ4 (0.30) | — | |
| SCHEMBL9978268 | 0.79 | MGAM (0.40) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL3177216 | 0.79 | HCAR2 (0.33) | — | |
| SCHEMBL7200816 | 0.79 | PYCR1 (0.38) | PYCR1 | |
| SCHEMBL468463 | 0.78 | KDM4E (0.34) | TSHRHSD17B10PYCR1 | |
| SCHEMBL3171091 | 0.78 | TSHR (0.37) | TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285270-B1 | A METHOD FOR PRODUCING 1-PROPARGYL-2,4-DIOXOIMIDAZOLIDINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-06-03 | — | — | EP | claimed |
| EP-0285270-A1 | A method for producing 1-propargyl-2,4-dioxoimidazolidine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-10-05 | — | — | EP | claimed |
| EP-2576588-A1 | METHODS FOR THE SYNTHESIS OF ALKYNE-CONTAINING DICARBA BRIDGES IN PEPTIDES | Syngene Limited (AU) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011146974-A1 | METHODS FOR THE SYNTHESIS OF ALKYNE-CONTAINING DICARBA BRIDGES IN PEPTIDES | MONASH UNIVERSITY (AU) | 2011-12-01 | — | — | WO | disclosed |
| US-7645607-B2 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-01-12 | — | — | US | disclosed |
| EP-1705252-B1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL CO (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-20060216806-A1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2006-09-28 | — | — | US | disclosed |
| EP-1705252-A1 | Method for producing optically active N-protected-propargylglycine | Sumitomo Chemical Company, Limited (JP) | 2006-09-27 | — | — | EP | disclosed |